BRENDA - Enzyme Database

Comparison of biochemical and immunological properties between rat and Nicotiana glutinosa ornithine decarboxylase

Lee, Y.S.; Cho, Y.D.; J. Biochem. Mol. Biol. 34, 408-414 (2001)
No PubMed abstract available

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
4.1.1.17
spermidine
1 mM, 211% activation
Nicotiana glutinosa
4.1.1.17
spermine
1 mM, 309% activation
Nicotiana glutinosa
Cloned(Commentary)
EC Number
Commentary
Organism
4.1.1.17
expression in Escherichia coli
Rattus norvegicus
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
4.1.1.17
4-chloromercuribenzoate
0.01 mM, complete inhibition
Nicotiana glutinosa
4.1.1.17
4-chloromercuribenzoate
0.01 mM, 99% inhibition
Rattus norvegicus
4.1.1.17
5,5'-dithiobis(2-nitrobenzoic acid)
0.01 mM, 99% inhibition
Nicotiana glutinosa
4.1.1.17
5,5'-dithiobis(2-nitrobenzoic acid)
0.01 mM, 98% inhibition
Rattus norvegicus
4.1.1.17
agmatine
1 mM, 77% inhibition
Nicotiana glutinosa
4.1.1.17
cadaverine
1 mM, 46% inhibition
Nicotiana glutinosa
4.1.1.17
ethyl[dimethylaminopropyl]carbodiimide
1.0 mM, 54% inhibition
Nicotiana glutinosa
4.1.1.17
ethyl[dimethylaminopropyl]carbodiimide
1.0 mM, 52% inhibition
Rattus norvegicus
4.1.1.17
MTA
1 mM, 70% inhibition
Rattus norvegicus
4.1.1.17
N-ethylmaleimide
0.01 mM, complete inhibition
Nicotiana glutinosa
4.1.1.17
N-ethylmaleimide
0.01 mM, 99% inhibition
Rattus norvegicus
4.1.1.17
Phenylglyoxal
1.0 mM, 36% inhibition
Nicotiana glutinosa
4.1.1.17
Phenylglyoxal
1.0 mM, 71% inhibition
Rattus norvegicus
4.1.1.17
putrescine
1 mM, 70% inhibition
Nicotiana glutinosa
4.1.1.17
putrescine
1 mM, 63% inhibition
Rattus norvegicus
4.1.1.17
Salicylaldehyde
1.0 mM, 98% inhibition
Nicotiana glutinosa
4.1.1.17
Salicylaldehyde
1.0 mM, 82% inhibition
Rattus norvegicus
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
4.1.1.17
46000
-
2 * 46000, SDS-PAGE
Nicotiana glutinosa
4.1.1.17
53000
-
2 * 53000, SDS-PAGE
Rattus norvegicus
4.1.1.17
92000
-
native PAGE
Nicotiana glutinosa
4.1.1.17
106000
-
native PAGE
Rattus norvegicus
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.1.1.17
L-ornithine
Nicotiana glutinosa
-
putrescine + CO2
-
Nicotiana glutinosa
?
4.1.1.17
L-ornithine
Rattus norvegicus
-
putrescine + CO2
-
Rattus norvegicus
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.1.1.17
Nicotiana glutinosa
Q9FPK5
-
-
4.1.1.17
Rattus norvegicus
P09057
-
-
Purification (Commentary)
EC Number
Commentary
Organism
4.1.1.17
recombinant ODC
Rattus norvegicus
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.1.1.17
L-ornithine
-
651824
Nicotiana glutinosa
putrescine + CO2
-
651824
Nicotiana glutinosa
?
4.1.1.17
L-ornithine
-
651824
Rattus norvegicus
putrescine + CO2
-
651824
Rattus norvegicus
?
Subunits
EC Number
Subunits
Commentary
Organism
4.1.1.17
dimer
2 * 46000, SDS-PAGE
Nicotiana glutinosa
4.1.1.17
dimer
2 * 53000, SDS-PAGE
Rattus norvegicus
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
4.1.1.17
pyridoxal 5'-phosphate
-
Nicotiana glutinosa
4.1.1.17
pyridoxal 5'-phosphate
-
Rattus norvegicus
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
4.1.1.17
spermidine
1 mM, 211% activation
Nicotiana glutinosa
4.1.1.17
spermine
1 mM, 309% activation
Nicotiana glutinosa
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
4.1.1.17
expression in Escherichia coli
Rattus norvegicus
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
4.1.1.17
pyridoxal 5'-phosphate
-
Nicotiana glutinosa
4.1.1.17
pyridoxal 5'-phosphate
-
Rattus norvegicus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
4.1.1.17
4-chloromercuribenzoate
0.01 mM, complete inhibition
Nicotiana glutinosa
4.1.1.17
4-chloromercuribenzoate
0.01 mM, 99% inhibition
Rattus norvegicus
4.1.1.17
5,5'-dithiobis(2-nitrobenzoic acid)
0.01 mM, 99% inhibition
Nicotiana glutinosa
4.1.1.17
5,5'-dithiobis(2-nitrobenzoic acid)
0.01 mM, 98% inhibition
Rattus norvegicus
4.1.1.17
agmatine
1 mM, 77% inhibition
Nicotiana glutinosa
4.1.1.17
cadaverine
1 mM, 46% inhibition
Nicotiana glutinosa
4.1.1.17
ethyl[dimethylaminopropyl]carbodiimide
1.0 mM, 54% inhibition
Nicotiana glutinosa
4.1.1.17
ethyl[dimethylaminopropyl]carbodiimide
1.0 mM, 52% inhibition
Rattus norvegicus
4.1.1.17
MTA
1 mM, 70% inhibition
Rattus norvegicus
4.1.1.17
N-ethylmaleimide
0.01 mM, complete inhibition
Nicotiana glutinosa
4.1.1.17
N-ethylmaleimide
0.01 mM, 99% inhibition
Rattus norvegicus
4.1.1.17
Phenylglyoxal
1.0 mM, 36% inhibition
Nicotiana glutinosa
4.1.1.17
Phenylglyoxal
1.0 mM, 71% inhibition
Rattus norvegicus
4.1.1.17
putrescine
1 mM, 70% inhibition
Nicotiana glutinosa
4.1.1.17
putrescine
1 mM, 63% inhibition
Rattus norvegicus
4.1.1.17
Salicylaldehyde
1.0 mM, 98% inhibition
Nicotiana glutinosa
4.1.1.17
Salicylaldehyde
1.0 mM, 82% inhibition
Rattus norvegicus
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
4.1.1.17
46000
-
2 * 46000, SDS-PAGE
Nicotiana glutinosa
4.1.1.17
53000
-
2 * 53000, SDS-PAGE
Rattus norvegicus
4.1.1.17
92000
-
native PAGE
Nicotiana glutinosa
4.1.1.17
106000
-
native PAGE
Rattus norvegicus
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.1.1.17
L-ornithine
Nicotiana glutinosa
-
putrescine + CO2
-
Nicotiana glutinosa
?
4.1.1.17
L-ornithine
Rattus norvegicus
-
putrescine + CO2
-
Rattus norvegicus
?
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
4.1.1.17
recombinant ODC
Rattus norvegicus
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.1.1.17
L-ornithine
-
651824
Nicotiana glutinosa
putrescine + CO2
-
651824
Nicotiana glutinosa
?
4.1.1.17
L-ornithine
-
651824
Rattus norvegicus
putrescine + CO2
-
651824
Rattus norvegicus
?
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
4.1.1.17
dimer
2 * 46000, SDS-PAGE
Nicotiana glutinosa
4.1.1.17
dimer
2 * 53000, SDS-PAGE
Rattus norvegicus