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Literature summary extracted from

  • Wrobel, C.; Schmidt, E.V.; Polymenis, M.
    CDC64 encodes cytoplasmic alanyl-tRNA synthetase, Ala1p, of Saccharomyces cerevisiae (1999), J. Bacteriol., 181, 7618-7620.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.1.1.7 gene cdc64, DNA sequence determination and analysis, gene maps to a locus between met7 and prt1 on chromosome XV, gene derepresses gcn4 expression, the cdc64-1 mutant strain can be complemented by expression of the wild-type enzyme Saccharomyces cerevisiae

Protein Variants

EC Number Protein Variants Comment Organism
6.1.1.7 additional information temperature-sensitive mutation cdc64-1 might affect charging of tRNAAla and thereby initiation of cell division, the mutation causes G1 arrest in yeast cells corresponding to a type II Start phenotype, the mutant strain can be complemented by expression of the wild-type enzyme Saccharomyces cerevisiae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.1.1.7 ATP + L-alanine + tRNAAla Saccharomyces cerevisiae
-
 AMP + diphosphate + L-alanyl-tRNAAla
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.1.1.7 Saccharomyces cerevisiae
-
 gene cdc64
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.1.7 ATP + L-alanine + tRNAAla
-
 Saccharomyces cerevisiae AMP + diphosphate + L-alanyl-tRNAAla
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.1.1.7 Ala-tRNA synthetase
-
 Saccharomyces cerevisiae
6.1.1.7 Alanine transfer RNA synthetase
-
 Saccharomyces cerevisiae
6.1.1.7 Alanine translase
-
 Saccharomyces cerevisiae
6.1.1.7 Alanine tRNA synthetase
-
 Saccharomyces cerevisiae
6.1.1.7 Alanine-transfer RNA ligase
-
 Saccharomyces cerevisiae
6.1.1.7 alanine-tRNA ligase
-
 Saccharomyces cerevisiae
6.1.1.7 Alanyl-transfer ribonucleate synthetase
-
 Saccharomyces cerevisiae
6.1.1.7 Alanyl-transfer ribonucleic acid synthetase
-
 Saccharomyces cerevisiae
6.1.1.7 Alanyl-transfer RNA synthetase
-
 Saccharomyces cerevisiae
6.1.1.7 Alanyl-tRNA synthetase
-
 Saccharomyces cerevisiae
6.1.1.7 AlaRS
-
 Saccharomyces cerevisiae
6.1.1.7 Synthase, alanyl-transfer ribonucleate
-
 Saccharomyces cerevisiae

Cofactor

EC Number Cofactor Comment Organism Structure
6.1.1.7 ATP
-
 Saccharomyces cerevisiae