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Literature summary extracted from
- Purification and properties of a histidine decarboxylase from Tetragenococcus muriaticus, a halophilic lactic acid bacterium (2002), J. Appl. Microbiol., 92, 1136-1142.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.1.22 | KCl | 50% inhibition at 1.5 M | Tetragenococcus muriaticus |  |
| 4.1.1.22 | NaCl | 50% inhibition at 1.5 M | Tetragenococcus muriaticus | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.1.1.22 | 0.74 | - |
L-histidine | - |
Tetragenococcus muriaticus | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.22 | 13400 | - |
alpha6beta6, 6 * 28800 + 6 * 13400, SDS-PAGE | Tetragenococcus muriaticus |
| 4.1.1.22 | 28800 | - |
alpha6beta6, 6 * 28800 + 6 * 13400, SDS-PAGE | Tetragenococcus muriaticus |
| 4.1.1.22 | 258000 | - |
gel filtration | Tetragenococcus muriaticus |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.1.22 | L-histidine | Tetragenococcus muriaticus | - |
histamine + CO2 | - |
? | |
| 4.1.1.22 | L-histidine | Tetragenococcus muriaticus JCM 10006T | - |
histamine + CO2 | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.1.1.22 | Tetragenococcus muriaticus | - |
JCM 10006T | - |
| 4.1.1.22 | Tetragenococcus muriaticus JCM 10006T | - |
JCM 10006T | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 4.1.1.22 | ammonium sulfate, anion-exchange column, hydroxyapatite column | Tetragenococcus muriaticus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.22 | 1.6 | - |
- |
Tetragenococcus muriaticus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.1.22 | L-histidine | - |
Tetragenococcus muriaticus | histamine + CO2 | - |
? | |
| 4.1.1.22 | L-histidine | - |
Tetragenococcus muriaticus JCM 10006T | histamine + CO2 | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 4.1.1.22 | dodecamer | alpha6beta6, 6 * 28800 + 6 * 13400, SDS-PAGE | Tetragenococcus muriaticus |
Temperature Stability [°C]
| EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.22 | 40 | - |
2% loss of activity after 20 min | Tetragenococcus muriaticus |
| 4.1.1.22 | 70 | - |
85% loss of activity after 20 min | Tetragenococcus muriaticus |
| 4.1.1.22 | 80 | - |
complete loss of activity after 20 min | Tetragenococcus muriaticus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.22 | 4.5 | 7 | - |
Tetragenococcus muriaticus |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.22 | 3.5 | 8 | 50% of maximal activity at pH 3.5 | Tetragenococcus muriaticus |
pI Value
| EC Number | Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|---|
| 4.1.1.22 | Tetragenococcus muriaticus | isoelectric focusing | 4.8 | 4.7 |
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