Literature summary extracted from

Zhang, X.; Harrison, D.H.; Cui, Q.
Functional specificities of methylglyoxal synthase and triosephosphate isomerase: a combined QM/MM analysis (2002), J. Am. Chem. Soc., 124, 14871-14878.

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.2.3.3	Escherichia coli	P0A731	-	-

Reaction

EC Number	Reaction	Comment	Organism	Reaction ID
4.2.3.3	glycerone phosphate = 2-oxopropanal + phosphate	catalytic mechanism	Escherichia coli	a

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.2.3.3	dihydroxyacetone phosphate	catalyzes the elimination reaction of DHAP, which leads to phosphate and the enol of methylglyoxal, which is subsequently tautomerized to methylglyoxal in solution	Escherichia coli	methylglyoxal + phosphate	-	?
4.2.3.3	additional information	enzyme dos no catalyze the elimination reaction with glyceraldehyde phosphate	Escherichia coli	?	-	?

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Release 2023.1 (January 2023)