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Literature summary extracted from

  • Yamakami, J.; Sakurai, E.; Kuramasu, A.; Yanai, K.; Watanabe, T.; Tanaka, Y.
    L-Histidine decarboxylase protein and activity in rat brain microvascular endothelial cells (2000), Inflamm. Res., 49, 231-235.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.22 (S)-alpha-fluoromethylhistidine 0.001 mM, complete inhibition Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.22 L-histidine Rattus norvegicus
-
 histamine + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.22 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.1.22 0.00000014
-
 HDC activity in cultured brain microvascular endothelial cells Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.22 L-histidine
-
 Rattus norvegicus histamine + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.22 HDC
-
 Rattus norvegicus