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Literature summary extracted from

  • Turner, A.J.; Tanzawa, K.
    Mammalian membrane metallopeptidases: NEP, ECE, KELL, and PEX (1997), FASEB J., 11, 355-364.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.24.B15 gene PEX mapps to chromosome region Xp22.1 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.24.B15 membrane bound Homo sapiens 16020
-
3.4.24.B15 additional information enzyme is possibly an ectoenzyme, membrane-spanning region towards the N-terminus Homo sapiens
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.24.B15 Zn2+ zinc-metalloprotease Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.24.B15 protein + H2O Homo sapiens participates in postsecretory processing, enzyme is involved in regulation of phosphate levels and in bone metabolism peptides
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.B15 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.B15 protein + H2O
-
Homo sapiens peptides
-
?
3.4.24.B15 protein + H2O participates in postsecretory processing, enzyme is involved in regulation of phosphate levels and in bone metabolism Homo sapiens peptides
-
?

Synonyms

EC Number Synonyms Comment Organism
3.4.24.B15 M13.091 Merops-ID Homo sapiens
3.4.24.B15 PEX
-
Homo sapiens
3.4.24.B15 vitamin D-resistant hypophosphatemic rickets protein
-
Homo sapiens
3.4.24.B15 X-linked hypophosphatemia protein
-
Homo sapiens