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Literature summary extracted from

  • Lazoura, E.; Campbell, W.; Yamaguchi, Y.; Kato, K.; Okada, N.; Okada, H.
    Rational structure-based design of a novel carboxypeptidase R inhibitor (2002), Chem. Biol., 9, 1129-1139.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.17.3 Guanidinoethylmercaptosuccinic acid
-
 Homo sapiens
3.4.17.3 additional information no inhibition by CKPAKNARC, i.e. CPI-2KR Homo sapiens
3.4.17.20 CKPAKNARC i.e. CPI-2KR Homo sapiens
3.4.17.20 Guanidinoethylmercaptosuccinic acid
-
 Homo sapiens
3.4.17.20 potato carboxypeptidase inhibitor
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.17.3 Homo sapiens
-
-
-
3.4.17.20 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.17.3 hippuryl-Arg + H2O
-
 Homo sapiens hippuric acid + Arg
-
 ?
3.4.17.20 hippuryl-Arg + H2O
-
 Homo sapiens hippuric acid + Arg
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
3.4.17.20 0.0000014
-
 potato carboxypeptidase inhibitor pH 7.5 Homo sapiens
3.4.17.20 0.0004071
-
 CKPAKNARC pH 7.5 Homo sapiens