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Literature summary extracted from

  • Masuda, R.; Sakiyama, H.; Nonaka, T.; Kwan, A.; Nakagawa, K.; Moriya, H.; Imajoh-Ohmi, S.; Honjo, M.; Yoshida, K.
    Establishment and characterization of tartrate-resistant acid phosphatase and alkaline phosphatase double positive cell lines (2001), Cell Tissue Res., 304, 351-359.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.1.3.1 analysis CCP-2 cells are an important tool for investigation of chondrooclastogenesis/osteoclastogenesis and endochondrial ossification Cricetulus griseus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.1 additional information tartrate-rsistant Cricetulus griseus
3.1.3.2 additional information no inhibition by tartrate Cricetinae

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.3.1 Mg2+
-
 Cricetulus griseus

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.1 Cricetulus griseus
-
 Syrian hamster
-
3.1.3.2 Cricetinae
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
3.1.3.1 a phosphate monoester + H2O = an alcohol + phosphate Wide specificity. Also catalyses transphosphorylations. Some enzymes hydrolyse diphosphate Cricetulus griseus
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.1 bone marrow cell culture Cricetulus griseus
-
3.1.3.1 cartilage humeral epiphyseal from 14-days-old hamsters Cricetulus griseus
-
3.1.3.1 CCP-2 cell morphologically macrophage-like cells cloned from bone marrow cells by coculturing bone marrow cells with chondrocytes, the CCP-2 cells are similar to osteoclast but not the same Cricetulus griseus
-
3.1.3.1 chondrocyte hypertrophic Cricetulus griseus
-
3.1.3.1 additional information located at the secondary ossification site of hamster humerus Cricetulus griseus
-
3.1.3.1 osteoblast cell surface Cricetulus griseus
-
3.1.3.2 CCP-2 cell morphologically macrophage-like cells are cloned from hamster bone marrow cells by coculturing bone marrow cells with hamster chondrocytes Cricetinae
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.1 4-nitrophenyl phosphate + H2O
-
 Cricetulus griseus 4-nitrophenol + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.3.1 alkaline phosphatase
-
 Cricetulus griseus
3.1.3.1 ALP
-
 Cricetulus griseus
3.1.3.2 tartrate-resistant acid phosphatase
-
 Cricetinae
3.1.3.2 TRAP
-
 Cricetinae

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.3.1 37
-
 assay at Cricetulus griseus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.3.1 9.5
-
 assay at Cricetulus griseus