BRENDA - Enzyme Database

The binding of Na(+) to apo-enolase permits the binding of substrate

Lin, T.; Kornblatt, M.J.; Biochim. Biophys. Acta 1476, 279-286 (2000)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
4.2.1.11
NaClO4
inactivation is due to dissociation of the enolase into inactive monomers, 2-phospho-D-glycerate prevents this inactivation
Oryctolagus cuniculus
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
4.2.1.11
Mg2+
three binding sites, binding at the first two is required for activity, binding at the third site is inhibitory
Oryctolagus cuniculus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.2.1.11
Oryctolagus cuniculus
-
rabbit
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
4.2.1.11
muscle
-
Oryctolagus cuniculus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.11
2-phospho-D-glycerate
-
650303
Oryctolagus cuniculus
phosphoenolpyruvate
-
650303
Oryctolagus cuniculus
r
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
4.2.1.11
NaClO4
inactivation is due to dissociation of the enolase into inactive monomers, 2-phospho-D-glycerate prevents this inactivation
Oryctolagus cuniculus
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
4.2.1.11
Mg2+
three binding sites, binding at the first two is required for activity, binding at the third site is inhibitory
Oryctolagus cuniculus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
4.2.1.11
muscle
-
Oryctolagus cuniculus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.11
2-phospho-D-glycerate
-
650303
Oryctolagus cuniculus
phosphoenolpyruvate
-
650303
Oryctolagus cuniculus
r