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Literature summary extracted from

  • Bienvenue, D.L.; Gilner, D.M.; Davis, R.S.; Bennett, B.; Holz, R.C.
    Substrate specificity, metal binding properties, and spectroscopic characterization of the DapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase from Haemophilus influenzae (2003), Biochemistry, 42, 10756-10763.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.5.1.18 0.26
-
 (2S,6S)-2-amino-6-[(3-carboxypropanoyl)amino]heptane-dioic acid pH 7.5, 30°C, ZnCo-loaded enzyme Haemophilus influenzae
3.5.1.18 0.73
-
 (2S,6S)-2-amino-6-[(3-carboxypropanoyl)amino]heptane-dioic acid pH 7.5, 30°C, Zn-loaded enzyme Haemophilus influenzae
3.5.1.18 0.73
-
 (2S,6S)-2-amino-6-[(3-carboxypropanoyl)amino]heptane-dioic acid pH 7.5, 30°C, ZnZn-loaded enzyme Haemophilus influenzae
3.5.1.18 0.74
-
 (2S,6S)-2-amino-6-[(3-carboxypropanoyl)amino]heptane-dioic acid pH 7.5, 30°C, CoZn-loaded enzyme Haemophilus influenzae
3.5.1.18 0.99
-
 (2S,6S)-2-amino-6-[(3-carboxypropanoyl)amino]heptane-dioic acid pH 7.5, 30°C, Co-loaded enzyme Haemophilus influenzae
3.5.1.18 0.99
-
 (2S,6S)-2-amino-6-[(3-carboxypropanoyl)amino]heptane-dioic acid pH 7.5, 30°C, CoCo-loaded enzyme Haemophilus influenzae

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.5.1.18 Cd2+ 65% of activity with Zn2+ Haemophilus influenzae
3.5.1.18 Co2+ 125% of activity with Zn2+ Haemophilus influenzae
3.5.1.18 Mn2+ 20% of activity with Zn2+ Haemophilus influenzae
3.5.1.18 Zn2+ 100% of activity Haemophilus influenzae

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.18 Haemophilus influenzae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.18 (2S,6S)-2-amino-6-[(3-carboxypropanoyl)amino]heptane-dioic acid high stereospecificity Haemophilus influenzae ?
-
 ?