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Literature summary extracted from

  • Hua, Z.C.
    Renaturation and purification of recombinant tissue-type plasminogen activator expressed in E. coli (1997), Biochem. Mol. Biol. Int., 41, 815-820.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.21.68 cDNA expressed in Escherichia coli in the form of inclusion body Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.68 plasminogen + H2O Homo sapiens critical role in fibrinolysis plasmin + ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.68 Homo sapiens
-
 human
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.4.21.68 glycoprotein
-
 Homo sapiens

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.21.68 recombinant enzyme Homo sapiens

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.21.68 additional information
-
 specific activity of 240000 I.U./mg protein Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.68 plasminogen + H2O
-
 Homo sapiens plasmin + ?
-
 ?
3.4.21.68 plasminogen + H2O critical role in fibrinolysis Homo sapiens plasmin + ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.68 Tissue-type plasminogen activator
-
 Homo sapiens