Literature summary extracted from

Vadon-Le Goff, S.; Delaforge, M.; Boucher, J.L.; Janosik, M.; Kraus, J.P.; Mansuy, D.
Coordination chemistry of the heme in cystathionine beta-synthase: formation of iron(II)-isonitrile complexes (2001), Biochem. Biophys. Res. Commun., 283, 487-492.

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.2.1.22	Homo sapiens	-	-	-
4.2.1.22	Rattus norvegicus	-	male Sprague-Dawley	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
4.2.1.22	liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.2.1.22	L-Serine + homocysteine	-	Homo sapiens	Cystathionine + H2O	-	?
4.2.1.22	L-Serine + homocysteine	-	Rattus norvegicus	Cystathionine + H2O	-	?

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
4.2.1.22	heme	ferrous CBS can form a complex with isonitriles	Homo sapiens
4.2.1.22	heme	ferruous CBS can form a complex with isonitriles	Rattus norvegicus

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Release 2023.1 (January 2023)