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Literature summary extracted from

  • Fischer, R.; Jensen, R.
    Arogenate dehydratase (1987), Methods Enzymol., 142, 495-502.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.1.91 beta-2-Thienylalanine
-
 Brevundimonas diminuta
4.2.1.91 L-phenylalanine feedback inhibition Brevundimonas diminuta
4.2.1.91 L-phenylalanine feedback inhibition Euglena gracilis
4.2.1.91 additional information not feedback inhibited by L-phenylalanine Pseudomonas aeruginosa
4.2.1.91 additional information not feedback inhibited by L-phenylalanine Xanthomonas campestris
4.2.1.91 p-Fluorophenylalanine
-
 Brevundimonas diminuta

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.2.1.91 0.63
-
 L-arogenate pH 7.5, 37°C, ATCC 13184 Brevundimonas diminuta

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.1.91 L-arogenate Euglena gracilis
-
 L-phenylalanine + CO2 + H2O
-
 ?
4.2.1.91 L-arogenate Pseudomonas aeruginosa
-
 L-phenylalanine + CO2 + H2O
-
 ?
4.2.1.91 L-arogenate Xanthomonas campestris
-
 L-phenylalanine + CO2 + H2O
-
 ?
4.2.1.91 L-arogenate Brevundimonas diminuta
-
 L-phenylalanine + CO2 + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.91 Brevundimonas diminuta
-
 ATCC 13184 and ATCC 11568
-
4.2.1.91 Euglena gracilis
-
-
-
4.2.1.91 Pseudomonas aeruginosa
-
-
-
4.2.1.91 Xanthomonas campestris
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.2.1.91 partially Euglena gracilis
4.2.1.91 partially Pseudomonas aeruginosa
4.2.1.91 partially Xanthomonas campestris
4.2.1.91 partially Brevundimonas diminuta

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.2.1.91 0.0063
-
 ATCC 13184 Brevundimonas diminuta

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.91 L-arogenate
-
 Euglena gracilis L-phenylalanine + CO2 + H2O
-
 ?
4.2.1.91 L-arogenate
-
 Pseudomonas aeruginosa L-phenylalanine + CO2 + H2O
-
 ?
4.2.1.91 L-arogenate
-
 Xanthomonas campestris L-phenylalanine + CO2 + H2O
-
 ?
4.2.1.91 L-arogenate
-
 Brevundimonas diminuta L-phenylalanine + CO2 + H2O
-
 ?
4.2.1.91 additional information does not accept prephenate as substrate Euglena gracilis ?
-
 ?
4.2.1.91 additional information does not accept prephenate as substrate Brevundimonas diminuta ?
-
 ?
4.2.1.91 prephenate
-
 Pseudomonas aeruginosa phenylpyruvate + CO2 + H2O
-
 ?
4.2.1.91 prephenate
-
 Xanthomonas campestris phenylpyruvate + CO2 + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.2.1.91 cyclohexadienyl dehydratase
-
 Pseudomonas aeruginosa
4.2.1.91 cyclohexadienyl dehydratase
-
 Xanthomonas campestris

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.2.1.91 7 8 ATCC 13184 Brevundimonas diminuta

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
4.2.1.91 8.2
-
 ATCC 13184, activity declines sharply above Brevundimonas diminuta