BRENDA - Enzyme Database show

Nitrile hydratase from Rhodococcus erythropolis: metabolization of steroidal compounds with a nitrile group

Kaufmann, G.; Dautzenberg, H.; Henkel, H.; Müller, G.; Schäfer, T.; Undeutsch, B.; Oettel, M.; Steroids 64, 535-540 (1999)

Data extracted from this reference:

Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.2.1.84
Rhodococcus erythropolis
-
-
-
4.2.1.84
Rhodococcus rhodochrous
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.84
17alpha-cyanomethyl-17beta-hydroxy-estra-4,9-dien-3-one + H2O
the steroidal group is metabolized very slowly
648445
Rhodococcus erythropolis
17alpha-acetamido-estra-1,3,5(10),9(11)-tetraene-3,17beta-diol
-
648445
Rhodococcus erythropolis
?
4.2.1.84
3-cyanopyridine + H2O
-
648445
Rhodococcus rhodochrous
pyridine-3-carbamide
i.e. nicotinamide
648445
Rhodococcus rhodochrous
?
4.2.1.84
3-cyanopyridine + H2O
-
648445
Rhodococcus erythropolis
pyridine-3-carbamide
i.e. nicotinamide
648445
Rhodococcus erythropolis
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.2.1.84
17alpha-cyanomethyl-17beta-hydroxy-estra-4,9-dien-3-one + H2O
the steroidal group is metabolized very slowly
648445
Rhodococcus erythropolis
17alpha-acetamido-estra-1,3,5(10),9(11)-tetraene-3,17beta-diol
-
648445
Rhodococcus erythropolis
?
4.2.1.84
3-cyanopyridine + H2O
-
648445
Rhodococcus rhodochrous
pyridine-3-carbamide
i.e. nicotinamide
648445
Rhodococcus rhodochrous
?
4.2.1.84
3-cyanopyridine + H2O
-
648445
Rhodococcus erythropolis
pyridine-3-carbamide
i.e. nicotinamide
648445
Rhodococcus erythropolis
-