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Literature summary extracted from

  • Brillard-Bourdet, M.; Rehault, S.; Juliano, L.; Ferrer, M.; Moreau, T.; Gauthier, F.
    Amidolytic activity of prostatic acid phosphatase on human semenogelins and semenogelin-derived synthetic substrates (2002), Eur. J. Biochem., 269, 390-395.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.77 polypeptide + H2O Homo sapiens
-
peptides
-
?
3.4.21.77 semenogelin + H2O Homo sapiens
-
semenogelin fractions
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.77 Homo sapiens
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
3.4.21.77 Preferential cleavage: -Tyr-/- enzyme is a serine protease Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.77 o-aminobenzoyl-ISYQSSSTEEQ ethylene diamine 2,4-dinitrophenyl + 2 H2O substrate is intramolecularly quenched Homo sapiens o-aminobenzoyl-ISYQ + SSST + EEQ ethylene diamine 2,4-dinitrophenyl
-
?
3.4.21.77 o-aminobenzoyl-ISYQSSSTEEQ ethylene diamine 2,4-dinitrophenyl + 2 H2O synthetic fluorogenic substrate, that encompasses a sequence containing a major ex vivo cleavage site , the Gln266-Ser267 bond of semenogelin I Homo sapiens o-aminobenzoyl-ISYQ + SSST + EEQ ethylene diamine 2,4-dinitrophenyl
-
?
3.4.21.77 polypeptide + H2O
-
Homo sapiens peptides
-
?
3.4.21.77 semenogelin + H2O
-
Homo sapiens semenogelin fragments
-
?
3.4.21.77 semenogelin + H2O
-
Homo sapiens semenogelin fractions
-
?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.77 K3
-
Homo sapiens
3.4.21.77 prostate-specific antigen
-
Homo sapiens