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Literature summary extracted from

  • Bailey, G.S.
    Rat pancreas kallikrein (1988), Methods Enzymol., 163, 115-128.
    View publication on PubMed

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.21.35 35900
-
 prokallikrein A, gel filtration Rattus norvegicus
3.4.21.35 36500
-
 1 * 36500, prokallikrein A, SDS-PAGE Rattus norvegicus
3.4.21.35 37400
-
 prokallikrein B, gel filtration Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.35 polypeptide + H2O Rattus norvegicus
-
 peptides
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.35 Rattus norvegicus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.4.21.35 proteolytic modification zymogen: prokallikrein Rattus norvegicus
3.4.21.35 proteolytic modification activation by trypsin Rattus norvegicus

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.21.35 prokallikrein A and B Rattus norvegicus
3.4.21.35 to homogeneity Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.21.35 315
-
 purified kallikrein A Rattus norvegicus
3.4.21.35 323
-
 purified kallikrein B Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.35 benzyloxycarbonyl-Arg methyl ester + H2O
-
 Rattus norvegicus benzyloxycarbonyl-Arg + methanol
-
 ?
3.4.21.35 Benzyloxycarbonyl-Lys methyl ester + H2O
-
 Rattus norvegicus Benzyloxycarbonyl-Lys + methanol
-
 ?
3.4.21.35 N-alpha-acetyl-Tyr ethyl ester + H2O
-
 Rattus norvegicus N-alpha-acetyl-Tyr + ethanol
-
 ?
3.4.21.35 N-alpha-benzoyl-L-Arg ethyl ester + H2O
-
 Rattus norvegicus N-alpha-benzoyl-L-Arg + ethanol
-
 ?
3.4.21.35 polypeptide + H2O
-
 Rattus norvegicus peptides
-
 ?
3.4.21.35 Tosyl-Arg methyl ester + H2O
-
 Rattus norvegicus Tosyl-Arg + methanol
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.21.35 monomer 1 * 36500, prokallikrein A, SDS-PAGE Rattus norvegicus
3.4.21.35 monomer 1* 38400, prokallikrein B, SDS-PAGE Rattus norvegicus