Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Nakayama, K.; Kim, W.S.; Nakagawa, T.; Nagahama, M; Murakami, K.
    Substrate specificity of prorenin converting enzyme of mouse submandibular gland. Analysis using site-directed mutagenesis (1990), J. Biol. Chem., 265, 21027-21031.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.119 polypeptide + H2O Mus musculus
-
 peptides
-
 ?
3.4.21.119 Prorenin + H2O Mus musculus inactive precursor Renin + ? product is an active enzyme ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.119 Mus musculus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.21.119
-
 Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.119 additional information
-
 Mus musculus
-
3.4.21.119 submandibular gland
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.119 additional information glycosylation near the processing site might prevent hydrolysis Mus musculus ?
-
 ?
3.4.21.119 additional information substrate specificty Mus musculus ?
-
 ?
3.4.21.119 polypeptide + H2O
-
 Mus musculus peptides
-
 ?
3.4.21.119 polypeptide + H2O cleavage site at paired basic amino acid residues Mus musculus peptides
-
 ?
3.4.21.119 Prorenin + H2O cleavage site at paired basic amino acid residues Mus musculus Renin + ?
-
 ?
3.4.21.119 Prorenin + H2O no cleavage of the peptide bond between Arg and Pro Mus musculus Renin + ?
-
 ?
3.4.21.119 Prorenin + H2O specifically cleaves the peptide bond on the COOH-side of the Arg residue at the Lys-Arg pair of mouse Ren 2 prorenin, but does not cleave mouse Ren 1 and human prorenins Mus musculus Renin + ?
-
 ?
3.4.21.119 Prorenin + H2O inactive precursor Mus musculus Renin + ? product is an active enzyme ?

Synonyms

EC Number Synonyms Comment Organism
3.4.21.119 PRECE
-
 Mus musculus
3.4.21.119 prorenin converting enzyme
-
 Mus musculus