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Literature summary extracted from

  • Cheng, T.C.; Harvey, S.P.; Chen, G.L.
    Cloning and expression of a gene encoding a bacterial enzyme for decontamination of organophosphorus nerve agents and nucleotide sequence of the enzyme (1996), Appl. Environ. Microbiol., 62, 1636-1641.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
3.1.8.2 degradation enzyme catalyse the hydrolysis of toxic organophosphorus cholinesterase-inhibiting compounds, including pesticides and chemical nerve agents Alteromonas sp.
3.1.8.2 degradation enzyme is capable of detoxifying chemical warfare agents by hydrolysis Alteromonas sp.

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.8.2 expression in Escherichia coli Alteromonas sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.8.2 additional information Alteromonas sp. the natural substrates for enzyme are unknown, enzyme may, in nature, be used in peptide metabolism ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.8.2 Alteromonas sp.
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 JD6.5, halophilic bacterium
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Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.8.2 300
-
-
 Alteromonas sp.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.8.2 diisopropyl fluorophosphate + H2O
-
 Alteromonas sp. diisopropyl phosphate + fluoride
-
 ?
3.1.8.2 additional information the natural substrates for enzyme are unknown, enzyme may, in nature, be used in peptide metabolism Alteromonas sp. ?
-
 ?