EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.3.62 | ATP | weak | Sus scrofa | |
3.1.3.62 | CTP | more effective inhibitor than GTP | Sus scrofa | |
3.1.3.62 | GTP | marked inhibition | Sus scrofa | |
3.1.3.62 | Inositol 1,3,4,5,6-pentakisphosphate | - |
Sus scrofa | |
3.1.3.62 | inositol 1,3,4-trisphosphate | mixed-type inhibition | Sus scrofa | |
3.1.3.62 | Inositol 1,4,5-trisphosphate | product inhibition kinetics | Sus scrofa | |
3.1.3.62 | inositol 3,4,5,6-tetrakisphosphate | commercially available with 12% inositol 2,4,5,6-tetrakisphosphate, from turkey erythrocytes, marked inhibition, linear mixed-type inhibition | Sus scrofa | |
3.1.3.62 | additional information | not inhibited by Mg2+, Ca2+, Li+, non-hydrolysable adenine, guanine nucleotides or deoxynucleotides | Sus scrofa | |
3.1.3.62 | UTP | more effective inhibitor than GTP | Sus scrofa |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.3.62 | 0.0004 | - |
D-myo-Inositol 1,3,4,5-tetrakisphosphate | - |
Sus scrofa |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.1.3.62 | soluble | - |
Sus scrofa | - |
- |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.1.3.62 | KCl | activation | Sus scrofa | |
3.1.3.62 | additional information | not activated by Ca2+ up to 1 mM or Mg2+ up to 30 mM | Sus scrofa |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.1.3.62 | 36000 | - |
gel filtration | Sus scrofa |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.3.62 | D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O | Sus scrofa | enzyme may be regulated by the intracellular concentrations of inositol tris- and tetrakisphosphates | D-myo-inositol 1,4,5-trisphosphate + phosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.3.62 | Sus scrofa | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.1.3.62 | partial | Sus scrofa |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.3.62 | brain | - |
Sus scrofa | - |
EC Number | Storage Stability | Organism |
---|---|---|
3.1.3.62 | -80°C, several months, stable | Sus scrofa |
3.1.3.62 | 4°C, within weeks, loss of activity | Sus scrofa |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.3.62 | D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O | - |
Sus scrofa | D-myo-inositol 1,4,5-trisphosphate + phosphate | - |
? | |
3.1.3.62 | D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O | enzyme may be regulated by the intracellular concentrations of inositol tris- and tetrakisphosphates | Sus scrofa | D-myo-inositol 1,4,5-trisphosphate + phosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.3.62 | More | may be identical with EC 3.1.3.65 | Sus scrofa |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.1.3.62 | 37 | - |
assay at | Sus scrofa |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.1.3.62 | 7.4 | - |
assay at | Sus scrofa |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.3.62 | 0.0005 | - |
inositol 3,4,5,6-tetrakisphosphate | pH 7.4, 37°C | Sus scrofa | |
3.1.3.62 | 0.00175 | - |
inositol 1,3,4-trisphosphate | pH 7.4, 37°C | Sus scrofa | |
3.1.3.62 | 0.002 | - |
Inositol 1,4,5-trisphosphate | pH 7.4, 37°C | Sus scrofa |