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Literature summary extracted from

  • Erneux, C.; Govaerts, C.; Communi, D.; Pesesse, X.
    The diversity and possible functions of the inositol polyphosphate 5-phosphatases (1998), Biochim. Biophys. Acta, 1436, 185-199.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.56 2,3-bisphosphoglycerate
-
 Homo sapiens
3.1.3.56 N-ethylmaleimide
-
 Homo sapiens
3.1.3.56 Phenylglyoxal Arg-343 and Arg-350 were found to be covalently modified; irreversible, substrates and 2,3-bisphosphoglycerate protect against inactivation Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.3.56 membrane membrane associated enzyme has lower specific activity than soluble enzyme Homo sapiens 16020
-
3.1.3.56 soluble
-
 Homo sapiens
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.3.56 Mg2+
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.3.56 D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O Homo sapiens
-
 D-myo-inositol 1,3,4-trisphosphate + phosphate
-
 ?
3.1.3.56 D-myo-inositol 1,4,5-trisphosphate + H2O Homo sapiens regulation of intracellular Ca2+ level by degradation of intracellular Ca2+ releasing second messenger D-myo-inositol 1,4,5-trisphosphate D-myo-inositol 1,4-bisphosphate + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.56 Homo sapiens
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.1.3.56 side-chain modification isoprenylation Homo sapiens
3.1.3.56 side-chain modification farnesylation Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.56 erythrocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.56 D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O
-
 Homo sapiens D-myo-inositol 1,3,4-trisphosphate + phosphate
-
 ?
3.1.3.56 D-myo-inositol 1,4,5-trisphosphate + H2O
-
 Homo sapiens D-myo-inositol 1,4-bisphosphate + phosphate
-
 ?
3.1.3.56 D-myo-inositol 1,4,5-trisphosphate + H2O regulation of intracellular Ca2+ level by degradation of intracellular Ca2+ releasing second messenger D-myo-inositol 1,4,5-trisphosphate Homo sapiens D-myo-inositol 1,4-bisphosphate + phosphate
-
 ?