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Literature summary extracted from

  • Yoshinari, K.; Nagata, K.; Shiraga, T.; Iwasaki, K.; Hata, T.; Ogino, M.; Ueda, R.; Fujita, K.; Shimada, M.; Yamazoe, Y.
    Molecular cloning, expression, and enzymatic characterization of rabbit hydroxysteroid sulfotransferase AST-RB2 (1998), J. Biochem., 123, 740-746.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.8.2.2 cloning of AST-RB2 (ST2A8) from cDNA library, expressed in Escherichia coli Oryctolagus cuniculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.8.2.2 cytosol
-
 Oryctolagus cuniculus 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.8.2.2 3'-phosphoadenylylsulfate + dehydroepiandrosterone Oryctolagus cuniculus activation and detoxification of hormones, neurotransmitters, drugs, and carcinogens adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.2 Oryctolagus cuniculus
-
 rabbit
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.8.2.2
-
 Oryctolagus cuniculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.2 3'-phosphoadenylylsulfate + dehydroepiandrosterone
-
 Oryctolagus cuniculus adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
 r
2.8.2.2 3'-phosphoadenylylsulfate + dehydroepiandrosterone activation and detoxification of hormones, neurotransmitters, drugs, and carcinogens Oryctolagus cuniculus adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
 r
2.8.2.2 3'-phosphoadenylylsulfate + testosterone
-
 Oryctolagus cuniculus adenosine 3',5'-bisphosphate + testosterone 3-sulfate
-
 r
2.8.2.2 additional information activation and detoxification of both endogenous and exogenous chemicals, isozyme AST-RB2 high activity to both hydroxysteroids and amines, no activity to lithocholate Oryctolagus cuniculus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.8.2.2 AST-RB2
-
 Oryctolagus cuniculus