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Literature summary extracted from

  • Momburg, M.; Stuhlsatz, H.W.; Greiling, H.
    Isolation and substrate specificity of a 3-phosphoadenyl sulfate: chondroitin 6-sulfotransferase from mouse liver (1972), Hoppe-Seyler's Z. Physiol. Chem., 353, 1351-1361.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.8.2.17 4-chloromercuribenzoate 1 mM Mus musculus
2.8.2.17 ADP 60% inhibition at 0.12 mM Mus musculus
2.8.2.17 AMP
-
 Mus musculus
2.8.2.17 ATP
-
 Mus musculus
2.8.2.17 heparin 40% inhibition in the nanomolar range Mus musculus
2.8.2.17 additional information not: iodoacetamide Mus musculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.8.2.17 0.018
-
 3'-phosphoadenylylsulfate pH 8.2, 37°C Mus musculus
2.8.2.17 0.06
-
 native chondroitin pH 8.2, 37°C Mus musculus
2.8.2.17 1.8
-
 Desulfated chondroitin sulfate pH 8.2, 37°C Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.17 Mus musculus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.8.2.17 partial Mus musculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.2.17 liver
-
 Mus musculus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.8.2.17 additional information
-
-
 Mus musculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.17 3'-phosphoadenylyl sulfate + native chondroitin
-
 Mus musculus adenosine 3',5'-bisphosphate + native chondroitin sulfate
-
 r
2.8.2.17 3'-phosphoadenylylsulfate + chondroitin native chondroitin is the best acceptor, chemically desulfated chondroitin sulfate has the lowest rate of sulfation Mus musculus adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate
-
 ?
2.8.2.17 adenosine 3',5'-bisphosphate + desulfated chondroitin sulfate
-
 Mus musculus 3'-phosphoadenylyl sulfate + desulfated chondroitin
-
 r
2.8.2.17 additional information no substrate: hyaluronate Mus musculus ?
-
 ?
2.8.2.17 additional information no substrate: heparin Mus musculus ?
-
 ?
2.8.2.17 additional information dermatan sulfate and keratan sulfate preparations which contain covalently bound chondroitin sulfate act as sulfate acceptors Mus musculus ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.8.2.17 8.2
-
-
 Mus musculus