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Literature summary extracted from

  • Forbes-Bamforth, K.J.; Coughtrie, M.W.H.
    Identification of a new adult human liver sulfotransferase with specificity for endogenous and xenobiotic estrogens (1994), Biochem. Biophys. Res. Commun., 198, 707-711.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.8.2.4 cytosol
-
 Homo sapiens 5829
-
2.8.2.15 cytosol
-
 Homo sapiens 5829
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.8.2.4 35000
-
 2 * 35000, immunoblot analysis Homo sapiens
2.8.2.15 33000
-
 immunoblot analysis, antibodies against rat liver sulfotransferases Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.8.2.4 3'-phosphoadenylylsulfate + estrone Homo sapiens
-
 adenosine 3',5'-bisphosphate + estrone 3-sulfate
-
 r
2.8.2.15 3'-phosphoadenylylsulfate + dehydroepiandrosterone Homo sapiens sulfation is an important pathway for biotransformation and inactivation of drugs, xenobiotics, monoamine and catecholamine neurotransmitters and steroid hormones adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.4 Homo sapiens
-
 human
-
2.8.2.15 Homo sapiens
-
 human
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.8.2.4
-
 Homo sapiens
2.8.2.15
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.2.4 liver
-
 Homo sapiens
-
2.8.2.15 liver isoenzyme in adult liver Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.4 3'-phosphoadenylylsulfate + 17alpha ethinyl estradiol
-
 Homo sapiens adenosine 3',5'-bisphosphate + 17alpha ethinyl estradiol 3-sulfate
-
 r
2.8.2.4 3'-phosphoadenylylsulfate + estrone
-
 Homo sapiens adenosine 3',5'-bisphosphate + estrone 3-sulfate
-
 r
2.8.2.15 3'-phosphoadenylylsulfate + dehydroepiandrosterone sulfation is an important pathway for biotransformation and inactivation of drugs, xenobiotics, monoamine and catecholamine neurotransmitters and steroid hormones Homo sapiens adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
 ?
2.8.2.15 3'-phosphoadenylylsulfate + estrone
-
 Homo sapiens adenosine 3',5'-bisphosphate + estrone sulfate
-
 r
2.8.2.15 additional information specific for endogenous and xenobiotic estrogens Homo sapiens ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.8.2.4 dimer 2 * 35000, immunoblot analysis Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
2.8.2.15 EST
-
 Homo sapiens