BRENDA - Enzyme Database show

Purification and immunochemical charcterization of a male-specific rat liver oestrogen sulphotransferase

Borthwick, E.B.; Burchell, A.; Coughtrie, M.W.H.; Biochem. J. 289, 719-725 (1993)
No PubMed abstract available

Data extracted from this reference:

Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
2.8.2.15
32500
-
gel filtration
Rattus norvegicus
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.8.2.15
3'-phosphoadenylylsulfate + dehydroepiandrosterone
Rattus norvegicus
major pathway in the metabolism of steroid hormones
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
Rattus norvegicus
r
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.8.2.15
Rattus norvegicus
-
rat; Wistar, male
-
Purification (Commentary)
EC Number
Commentary
Organism
2.8.2.15
male-specific enzyme
Rattus norvegicus
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.8.2.15
brain
-
Rattus norvegicus
-
2.8.2.15
kidney
-
Rattus norvegicus
-
2.8.2.15
liver
-
Rattus norvegicus
-
Specific Activity [micromol/min/mg]
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
2.8.2.15
0.0035
-
-
Rattus norvegicus
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.8.2.15
3'-phosphoadenylylsulfate + 17beta-estradiol
-
645730
Rattus norvegicus
adenosine 3',5'-bisphosphate + ?
-
-
-
r
2.8.2.15
3'-phosphoadenylylsulfate + 2-naphthol
-
645730
Rattus norvegicus
adenosine 3',5'-bisphosphate + 2-naphthyl sulfate
-
-
-
r
2.8.2.15
3'-phosphoadenylylsulfate + dehydroepiandrosterone
-
645730
Rattus norvegicus
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
645730
Rattus norvegicus
r
2.8.2.15
3'-phosphoadenylylsulfate + dehydroepiandrosterone
major pathway in the metabolism of steroid hormones
645730
Rattus norvegicus
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
645730
Rattus norvegicus
r
2.8.2.15
3'-phosphoadenylylsulfate + estriol
-
645730
Rattus norvegicus
adenosine 3',5'-bisphosphate + estriol sulfate
-
645730
Rattus norvegicus
r
2.8.2.15
3'-phosphoadenylylsulfate + estrone
-
645730
Rattus norvegicus
adenosine 3',5'-bisphosphate + estrone sulfate
-
645730
Rattus norvegicus
r
2.8.2.15
3'-phosphoadenylylsulfate + pregnenolone
-
645730
Rattus norvegicus
adenosine 3',5'-bisphosphate + pregnenolone sulfate
-
645730
Rattus norvegicus
r
2.8.2.15
3'-phosphoadenylylsulfate + testosterone
-
645730
Rattus norvegicus
adenosine 3',5'-bisphosphate + testosterone sulfate
-
645730
Rattus norvegicus
r
2.8.2.15
additional information
not active towards androgens
645730
Rattus norvegicus
?
-
-
-
-
Subunits
EC Number
Subunits
Commentary
Organism
2.8.2.15
monomer
1 * 32500, SDS-PAGE
Rattus norvegicus
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
2.8.2.15
32500
-
gel filtration
Rattus norvegicus
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.8.2.15
3'-phosphoadenylylsulfate + dehydroepiandrosterone
Rattus norvegicus
major pathway in the metabolism of steroid hormones
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
Rattus norvegicus
r
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
2.8.2.15
male-specific enzyme
Rattus norvegicus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.8.2.15
brain
-
Rattus norvegicus
-
2.8.2.15
kidney
-
Rattus norvegicus
-
2.8.2.15
liver
-
Rattus norvegicus
-
Specific Activity [micromol/min/mg] (protein specific)
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
2.8.2.15
0.0035
-
-
Rattus norvegicus
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.8.2.15
3'-phosphoadenylylsulfate + 17beta-estradiol
-
645730
Rattus norvegicus
adenosine 3',5'-bisphosphate + ?
-
-
-
r
2.8.2.15
3'-phosphoadenylylsulfate + 2-naphthol
-
645730
Rattus norvegicus
adenosine 3',5'-bisphosphate + 2-naphthyl sulfate
-
-
-
r
2.8.2.15
3'-phosphoadenylylsulfate + dehydroepiandrosterone
-
645730
Rattus norvegicus
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
645730
Rattus norvegicus
r
2.8.2.15
3'-phosphoadenylylsulfate + dehydroepiandrosterone
major pathway in the metabolism of steroid hormones
645730
Rattus norvegicus
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
645730
Rattus norvegicus
r
2.8.2.15
3'-phosphoadenylylsulfate + estriol
-
645730
Rattus norvegicus
adenosine 3',5'-bisphosphate + estriol sulfate
-
645730
Rattus norvegicus
r
2.8.2.15
3'-phosphoadenylylsulfate + estrone
-
645730
Rattus norvegicus
adenosine 3',5'-bisphosphate + estrone sulfate
-
645730
Rattus norvegicus
r
2.8.2.15
3'-phosphoadenylylsulfate + pregnenolone
-
645730
Rattus norvegicus
adenosine 3',5'-bisphosphate + pregnenolone sulfate
-
645730
Rattus norvegicus
r
2.8.2.15
3'-phosphoadenylylsulfate + testosterone
-
645730
Rattus norvegicus
adenosine 3',5'-bisphosphate + testosterone sulfate
-
645730
Rattus norvegicus
r
2.8.2.15
additional information
not active towards androgens
645730
Rattus norvegicus
?
-
-
-
-
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
2.8.2.15
monomer
1 * 32500, SDS-PAGE
Rattus norvegicus