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Literature summary extracted from

  • Borthwick, E.B.; Burchell, A.; Coughtrie, M.W.H.
    Purification and immunochemical charcterization of a male-specific rat liver oestrogen sulphotransferase (1993), Biochem. J., 289, 719-725.
No PubMed abstract available

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.8.2.15 32500
-
 gel filtration Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.8.2.15 3'-phosphoadenylylsulfate + dehydroepiandrosterone Rattus norvegicus major pathway in the metabolism of steroid hormones adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.15 Rattus norvegicus
-
 rat
-
2.8.2.15 Rattus norvegicus
-
 Wistar, male
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.8.2.15 male-specific enzyme Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.2.15 brain
-
 Rattus norvegicus
-
2.8.2.15 kidney
-
 Rattus norvegicus
-
2.8.2.15 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.8.2.15 0.0035
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.15 3'-phosphoadenylylsulfate + 17beta-estradiol
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + ?
-
 r
2.8.2.15 3'-phosphoadenylylsulfate + 2-naphthol
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + 2-naphthyl sulfate
-
 r
2.8.2.15 3'-phosphoadenylylsulfate + dehydroepiandrosterone
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
 r
2.8.2.15 3'-phosphoadenylylsulfate + dehydroepiandrosterone major pathway in the metabolism of steroid hormones Rattus norvegicus adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
 r
2.8.2.15 3'-phosphoadenylylsulfate + estriol
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + estriol sulfate
-
 r
2.8.2.15 3'-phosphoadenylylsulfate + estrone
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + estrone sulfate
-
 r
2.8.2.15 3'-phosphoadenylylsulfate + pregnenolone
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + pregnenolone sulfate
-
 r
2.8.2.15 3'-phosphoadenylylsulfate + testosterone
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + testosterone sulfate
-
 r
2.8.2.15 additional information not active towards androgens Rattus norvegicus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.8.2.15 monomer 1 * 32500, SDS-PAGE Rattus norvegicus