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Literature summary extracted from

  • Ganguly, T.C.; Krasnykh, V.; Falany, C.N.
    Bacterial expression and kinetic characterization of the human monoamine-sulfating form of phenol sulfotransferase (1995), Drug Metab. Dispos., 23, 945-950.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.8.2.1 M-PST, functional expression in Escherichia coli Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.8.2.1 cytosol M-PST Homo sapiens 5829
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.8.2.1 33000
-
 x * 33000, recombinant M-PST Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.1 Homo sapiens
-
 2 forms: simple phenol sulfating P-PST, monoamine sulfating M-PST
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.2.1 brain M-PST Homo sapiens
-
2.8.2.1 intestine M-PST Homo sapiens
-
2.8.2.1 platelet M-PST Homo sapiens
-
2.8.2.1 T47D cell M-PST Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.1 3'-phosphoadenylyl sulfate + a phenol
-
 Homo sapiens adenosine 3',5'-bisphosphate + an aryl sulfate
-
 ?
2.8.2.1 3'-phosphoadenylylsulfate + 1-naphthol M-PST Homo sapiens adenosine 3',5'-bisphosphate + 1-naphthyl sulfate
-
 ?
2.8.2.1 3'-phosphoadenylylsulfate + 4-nitrophenol M-PST Homo sapiens adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
-
 ?
2.8.2.1 3'-phosphoadenylylsulfate + acetaminophen M-PST and P-PST Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?
2.8.2.1 3'-phosphoadenylylsulfate + dopamine M-PST Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?
2.8.2.1 3'-phosphoadenylylsulfate + epinephrine M-PST Homo sapiens adenosine 3',5'-bisphosphate + epinephrine sulfate
-
 ?
2.8.2.1 3'-phosphoadenylylsulfate + epinephrine P-PST Homo sapiens adenosine 3',5'-bisphosphate + epinephrine sulfate
-
 ?
2.8.2.1 3'-phosphoadenylylsulfate + minoxidil P-PST Homo sapiens adenosine 3',5'-bisphosphate + minoxidil sulfate
-
 ?
2.8.2.1 additional information substrate specificity Homo sapiens ?
-
 ?
2.8.2.1 additional information estrogens and related compounds are substrate only for P-PST Homo sapiens ?
-
 ?
2.8.2.1 additional information sterol-like structures cannot bind to M-PST Homo sapiens ?
-
 ?
2.8.2.1 additional information hydroxysteroids are no substrates Homo sapiens ?
-
 ?
2.8.2.1 additional information M-PST shows no activity with phentolamine Homo sapiens ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.8.2.1 ? x * 33000, recombinant M-PST Homo sapiens