Literature summary extracted from

Zhao, K.W.; Yeh, R.; Miller, A.L.
Purification and characterization of human lymphoblast N-acetylglucosamine-1-phosphotransferase (1992), Glycobiology, 2, 119-125.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
2.7.8.17	Tergitol NP-10	required	Homo sapiens

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.7.8.17	phosphatidic acid	-	Homo sapiens
2.7.8.17	phosphatidylglycerol	-	Homo sapiens
2.7.8.17	phosphatidylserine	-	Homo sapiens
2.7.8.17	UDP	-	Homo sapiens

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
2.7.8.17	0.024	-	UDP-GlcNAc	-	Homo sapiens
2.7.8.17	0.117	-	methyl-alpha-D-mannoside	-	Homo sapiens

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
2.7.8.17	Mg2+	divalent cation Mn2+ or Mg2+ is required	Homo sapiens
2.7.8.17	Mn2+	divalent cation, Mn2+ or Mg2+ is required	Homo sapiens

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
2.7.8.17	1000000	-	-	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.8.17	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.7.8.17	lymphoblast	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.8.17	UDP-N-acetyl-D-glucosamine + methyl-alpha-D-mannoside	-	Homo sapiens	UMP + N-acetyl-D-glucosamine-phospho-(methyl-alpha-D-mannoside)	-	?

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
2.7.8.17	7.2	7.5	-	Homo sapiens

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Release 2023.1 (January 2023)