BRENDA - Enzyme Database

Purification and characterization of human lymphoblast N-acetylglucosamine-1-phosphotransferase

Zhao, K.W.; Yeh, R.; Miller, A.L.; Glycobiology 2, 119-125 (1992)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
2.7.8.17
Tergitol NP-10
required
Homo sapiens
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.8.17
phosphatidic acid
-
Homo sapiens
2.7.8.17
phosphatidylglycerol
-
Homo sapiens
2.7.8.17
phosphatidylserine
-
Homo sapiens
2.7.8.17
UDP
-
Homo sapiens
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.7.8.17
0.024
-
UDP-GlcNAc
-
Homo sapiens
2.7.8.17
0.117
-
methyl-alpha-D-mannoside
-
Homo sapiens
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
2.7.8.17
Mg2+
divalent cation Mn2+ or Mg2+ is required
Homo sapiens
2.7.8.17
Mn2+
divalent cation, Mn2+ or Mg2+ is required
Homo sapiens
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
2.7.8.17
1000000
-
-
Homo sapiens
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.7.8.17
Homo sapiens
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.8.17
lymphoblast
-
Homo sapiens
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.8.17
UDP-N-acetyl-D-glucosamine + methyl-alpha-D-mannoside
-
645369
Homo sapiens
UMP + N-acetyl-D-glucosamine-phospho-(methyl-alpha-D-mannoside)
-
-
-
-
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.7.8.17
7.2
7.5
-
Homo sapiens
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
2.7.8.17
Tergitol NP-10
required
Homo sapiens
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.8.17
phosphatidic acid
-
Homo sapiens
2.7.8.17
phosphatidylglycerol
-
Homo sapiens
2.7.8.17
phosphatidylserine
-
Homo sapiens
2.7.8.17
UDP
-
Homo sapiens
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.7.8.17
0.024
-
UDP-GlcNAc
-
Homo sapiens
2.7.8.17
0.117
-
methyl-alpha-D-mannoside
-
Homo sapiens
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
2.7.8.17
Mg2+
divalent cation Mn2+ or Mg2+ is required
Homo sapiens
2.7.8.17
Mn2+
divalent cation, Mn2+ or Mg2+ is required
Homo sapiens
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
2.7.8.17
1000000
-
-
Homo sapiens
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.8.17
lymphoblast
-
Homo sapiens
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.8.17
UDP-N-acetyl-D-glucosamine + methyl-alpha-D-mannoside
-
645369
Homo sapiens
UMP + N-acetyl-D-glucosamine-phospho-(methyl-alpha-D-mannoside)
-
-
-
-
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.7.8.17
7.2
7.5
-
Homo sapiens