Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Dan, N.; Lehrman, M.A.
    Oligomerization of hamster UDP-GlcNAc:dolichol-P GlcNAc-1-P transferase, an enzyme with multiple transmembrane spans (1997), J. Biol. Chem., 272, 14214-14219.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
2.7.8.15 R303K catalytically inactive mutant enzyme, this mutant can be expressed in CHO-K1 cells and can bind tunicamycin efficiently, indicative of proper folding. The R303K mutant can inhibit exogenously expressed normal enzyme Cricetulus griseus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.8.15 endoplasmic reticulum an enzyme with multiple transmembrane spans Cricetulus griseus 5783
-
2.7.8.15 membrane enzyme with multiple transmembrane spans Cricetulus griseus 16020
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.8.15 34000
-
 2 * 34000, the 67000 Da enzyme form is a homodimer of UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase or perhaps a hetero-oligomer with another microsomal component Cricetulus griseus

Organism

EC Number Organism UniProt Comment Textmining
2.7.8.15 Cricetulus griseus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.8.15 CHO cell
-
 Cricetulus griseus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.8.15 UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
-
 Cricetulus griseus UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.8.15 dimer 2 * 34000, the 67000 Da enzyme form is a homodimer of UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase or perhaps a hetero-oligomer with another microsomal component Cricetulus griseus