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Literature summary extracted from

  • Zara, J.; Lehrman, M.A.
    Role of the carboxyl terminus in stable expression of hamster UDP-GlcNAc:dolichol-P GlcNAc-1-P transferase (1994), J. Biol. Chem., 269, 19108-19115.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
2.7.8.15 DELTA395-408 mutation fully eliminates enzyme expression in vivo Cricetulus griseus
2.7.8.15 DELTA398-408 removal of the last 11 amino acids 398-408 from the enzyme has no significant effect on the catalytic activity, thermal stability, tunicamycin binding, reticular localization, or consumption of cellular dolichol phosphate Cricetulus griseus
2.7.8.15 F395L/S396M/I397W expression of the mutant enzyme Cricetulus griseus
2.7.8.15 F395L/S396M/I397W/DELTA398-408 mutation fully eliminates enzyme expression in vivo Cricetulus griseus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.8.15 endoplasmic reticulum
-
 Cricetulus griseus 5783
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.8.15 UDP-N-acetyl-D-glucosamine + dolichyl phosphate Cricetulus griseus the enzyme catalyzes the committed step for N-linked glycosylation ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.8.15 Cricetulus griseus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.8.15 CHO cell
-
 Cricetulus griseus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.8.15 UDP-N-acetyl-alpha-D-glucosamine + dolichyl phosphate
-
 Cricetulus griseus UMP + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
 ?
2.7.8.15 UDP-N-acetyl-D-glucosamine + dolichyl phosphate the enzyme catalyzes the committed step for N-linked glycosylation Cricetulus griseus ?
-
 ?