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Literature summary extracted from
- Phosphatidylinositol synthesis in castor bean endosperm (1978), Plant Physiol., 62, 978-980.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 2.7.8.11 | CDP-dipalmitoylglyceride | above 1.2 mM | Ricinus communis |  |
| 2.7.8.11 | Triton X-100 | inhibits at all concentrations tested | Ricinus communis | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 2.7.8.11 | 0.3 | - |
myo-inositol | pH 8.5, 37°C | Ricinus communis | |
| 2.7.8.11 | 1.35 | - |
CDP-dipalmitoylglyceride | pH 8.5, 37°C | Ricinus communis | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 2.7.8.11 | endoplasmic reticulum | - |
Ricinus communis | 5783 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 2.7.8.11 | Mn2+ | - |
Ricinus communis | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.7.8.11 | CDP-diacylglycerol + myo-inositol | Ricinus communis | enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol | CMP + phosphatidyl-1D-myo-inositol | - |
r | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 2.7.8.11 | Ricinus communis | - |
castor bean | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 2.7.8.11 | endosperm | - |
Ricinus communis | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 2.7.8.11 | CDP-diacylglycerol + myo-inositol | - |
Ricinus communis | CMP + phosphatidyl-1D-myo-inositol | - |
r | |
| 2.7.8.11 | CDP-diacylglycerol + myo-inositol | enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol | Ricinus communis | CMP + phosphatidyl-1D-myo-inositol | - |
r | |
| 2.7.8.11 | CDP-dipalmitoylglyceride + myo-inositol | - |
Ricinus communis | ? | - |
? | |
| 2.7.8.11 | additional information | enzyme also catalyzes diacylglycerol-independent exchange reaction between phosphatidylinositol and inositol | Ricinus communis | ? | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 2.7.8.11 | 8.5 | - |
- |
Ricinus communis |
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