EC Number | General Stability | Organism |
---|---|---|
2.7.8.11 | inactivation caused by repeated freezing and thawing or by contact with detergent is prevented by addition of dithiothreitol and CDPdiacyl-sn-glycerol | Rattus norvegicus |
2.7.8.11 | loses activity when the lipids are removed | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.8.11 | bovine serum albumin | slight inhibition | Rattus norvegicus | |
2.7.8.11 | cetyltrimethylammonium bromide | strong inhibition | Rattus norvegicus | |
2.7.8.11 | iodoacetamide | - |
Rattus norvegicus | |
2.7.8.11 | iodoacetate | - |
Rattus norvegicus | |
2.7.8.11 | p-chloromercuribenzene sulfonate | - |
Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.7.8.11 | membrane | membrane-bound | Rattus norvegicus | 16020 | - |
2.7.8.11 | microsome | - |
Rattus norvegicus | - |
- |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.7.8.11 | 300000 | - |
partially purified enzyme, ultrafiltration | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.8.11 | CDP-diacylglycerol + myo-inositol | Rattus norvegicus | enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol | CMP + phosphatidyl-1D-myo-inositol | - |
r |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.8.11 | Rattus norvegicus | - |
rat | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.7.8.11 | partial | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.8.11 | brain | cerebral hemisphere | Rattus norvegicus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.7.8.11 | 1.233 | - |
- |
Rattus norvegicus |
EC Number | Storage Stability | Organism |
---|---|---|
2.7.8.11 | -20°C, substrate and dithioerythritol protects the enzyme activity for several days | Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.8.11 | CDP-diacylglycerol + myo-inositol | - |
Rattus norvegicus | CMP + phosphatidyl-1D-myo-inositol | - |
r | |
2.7.8.11 | CDP-diacylglycerol + myo-inositol | enzyme catalyzes the final step of de novo synthesis of phosphatidylinositol | Rattus norvegicus | CMP + phosphatidyl-1D-myo-inositol | - |
r |