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Literature summary extracted from

  • Revilla-Nuin, B.; Reglero, A.; Feo, J.C.; Rodriguez-Aparicio, L.B.; Ferrero, M.A.
    Identification, expression and tissue distribution of cytidine 5'-monophosphate N-acetylneuraminic acid synthetase activity in the rat (1998), Glycoconj. J., 15, 233-241.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.43 CTP + N-acylneuraminate Rattus norvegicus changes in the level of sialylation during development are intimately related to variations in the expression of the enzyme, at least in brain, heart, kidney, stomach, intestine and lung diphosphate + CMP-N-acylneuraminate
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?

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.43 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.7.43
-
Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.43 brain
-
Rattus norvegicus
-
2.7.7.43 heart
-
Rattus norvegicus
-
2.7.7.43 intestine
-
Rattus norvegicus
-
2.7.7.43 kidney
-
Rattus norvegicus
-
2.7.7.43 liver
-
Rattus norvegicus
-
2.7.7.43 lung
-
Rattus norvegicus
-
2.7.7.43 additional information no activity in skeletal muscle. The expression the enzyme is tissue-dependent and does not seem to be embryonically determined. Changes in the level of sialylation during development are intimately related to variations in the expression of the enzyme, at least in brain, heart, kidney, stomach, intestine and lung Rattus norvegicus
-
2.7.7.43 prostate
-
Rattus norvegicus
-
2.7.7.43 spleen
-
Rattus norvegicus
-
2.7.7.43 stomach
-
Rattus norvegicus
-
2.7.7.43 thymus
-
Rattus norvegicus
-
2.7.7.43 urinary bladder
-
Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.43 CTP + N-acylneuraminate
-
Rattus norvegicus diphosphate + CMP-N-acylneuraminate
-
?
2.7.7.43 CTP + N-acylneuraminate changes in the level of sialylation during development are intimately related to variations in the expression of the enzyme, at least in brain, heart, kidney, stomach, intestine and lung Rattus norvegicus diphosphate + CMP-N-acylneuraminate
-
?