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Literature summary extracted from

  • Schauer, R.; Wember, M.
    Studies on the substrate specificity of acylneuraminate cytidylyltransferase and sialytransferase of submandibular glands from cow, pig and horse (1973), Hoppe-Seyler's Z. Physiol. Chem., 354, 1405-1414.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.7.43 1.1
-
 N-acetyl-7(8)-O-acetylneuraminate 37°C, crude enzyme extract Bos taurus
2.7.7.43 1.1
-
 N-acetyl-7(8)-O-acetylneuraminate 37°C, crude enzyme extract Equus caballus
2.7.7.43 1.2
-
 N-acetylneuraminate
-
 Equus caballus
2.7.7.43 1.2
-
 N-acetylneuraminate 37°C, crude enzyme extract Bos taurus
2.7.7.43 1.2
-
 N-glycolylneuraminate 37°C, crude enzyme extract Bos taurus
2.7.7.43 1.2
-
 N-acetyl-4-O-acetylneuraminate 37°C, crude enzyme extract Equus caballus
2.7.7.43 1.3
-
 N-glycolylneuraminate 37°C, crude enzyme extract Equus caballus
2.7.7.43 1.3
-
 N-acetyl-4-O-acetylneuraminate 37°C, crude enzyme extract Sus scrofa
2.7.7.43 1.4
-
 N-acetylneuraminate
-
 Sus scrofa
2.7.7.43 1.4
-
 N-acetylneuraminate 37°C, crude enzyme extract Bos taurus
2.7.7.43 1.4
-
 N-acetyl-4-O-acetylneuraminate 37°C, crude enzyme extract Bos taurus
2.7.7.43 1.5
-
 N-glycolylneuraminate 37°C, crude enzyme extract Sus scrofa
2.7.7.43 1.6
-
 N-acetyl-7(8)-O-acetylneuraminate 37°C, crude enzyme extract Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.43 Bos taurus
-
-
-
2.7.7.43 Equus caballus
-
-
-
2.7.7.43 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.43 submandibular gland
-
 Sus scrofa
-
2.7.7.43 submandibular gland
-
 Bos taurus
-
2.7.7.43 submandibular gland
-
 Equus caballus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.43 CTP + N-acylneuraminate
-
 Sus scrofa diphosphate + CMP-N-acylneuraminate
-
 ?
2.7.7.43 CTP + N-acylneuraminate
-
 Bos taurus diphosphate + CMP-N-acylneuraminate
-
 ?
2.7.7.43 CTP + N-acylneuraminate
-
 Equus caballus diphosphate + CMP-N-acylneuraminate
-
 ?
2.7.7.43 CTP + N-glycolylneuraminate
-
 Sus scrofa diphosphate + CMP-N-glycolylneuraminate
-
 ?
2.7.7.43 CTP + N-glycolylneuraminate
-
 Bos taurus diphosphate + CMP-N-glycolylneuraminate
-
 ?
2.7.7.43 CTP + N-glycolylneuraminate
-
 Equus caballus diphosphate + CMP-N-glycolylneuraminate
-
 ?
2.7.7.43 fluoroacetylneuraminate + CTP
-
 Sus scrofa diphosphate + CMP-N-fluoroacetylneuraminate
-
 ?
2.7.7.43 fluoroacetylneuraminate + CTP
-
 Bos taurus diphosphate + CMP-N-fluoroacetylneuraminate
-
 ?
2.7.7.43 fluoroacetylneuraminate + CTP
-
 Equus caballus diphosphate + CMP-N-fluoroacetylneuraminate
-
 ?
2.7.7.43 N-acetyl-4-O-acetylneuraminate + CTP
-
 Sus scrofa diphosphate + CMP-N-acetyl-4-O-acetylneuraminate
-
 ?
2.7.7.43 N-acetyl-4-O-acetylneuraminate + CTP
-
 Bos taurus diphosphate + CMP-N-acetyl-4-O-acetylneuraminate
-
 ?
2.7.7.43 N-acetyl-4-O-acetylneuraminate + CTP
-
 Equus caballus diphosphate + CMP-N-acetyl-4-O-acetylneuraminate
-
 ?
2.7.7.43 N-acetyl-7(8)-O-acetylneuraminate + CTP
-
 Sus scrofa diphosphate + CMP-N-acetyl-7(8)-O-acetylneuraminate
-
 ?
2.7.7.43 N-acetyl-7(8)-O-acetylneuraminate + CTP
-
 Bos taurus diphosphate + CMP-N-acetyl-7(8)-O-acetylneuraminate
-
 ?
2.7.7.43 N-acetyl-7(8)-O-acetylneuraminate + CTP
-
 Equus caballus diphosphate + CMP-N-acetyl-7(8)-O-acetylneuraminate
-
 ?
2.7.7.43 N-chloroacetylneuraminate + CTP
-
 Sus scrofa diphosphate + CMP-N-chloroacetylneuraminate
-
 ?
2.7.7.43 N-chloroacetylneuraminate + CTP
-
 Bos taurus diphosphate + CMP-N-chloroacetylneuraminate
-
 ?
2.7.7.43 N-chloroacetylneuraminate + CTP
-
 Equus caballus diphosphate + CMP-N-chloroacetylneuraminate
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.7.43 9.5
-
-
 Bos taurus