Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Amick, G.D.; Reddy, S.A.G.; Damuni, Z.
    Protein phosphatase 2A is a specific protamine-kinase-inactivating phosphatase (1992), Biochem. J., 287, 1019-1022.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.1 additional information protein phosphatase 2B, 2C, catalytic subunit of protein phosphatase 1, protein tyrosine phosphatases (PTPase 1B and T-cell PTPase), pyruvate dehydrogenase phosphatase Bos taurus
2.7.11.1 Protein phosphatase 1b weak Bos taurus
2.7.11.1 Protein phosphatase 2A ATP; diphosphate; Mn2+ enhances inactivation rate; okadaic acid, microcystin-LR; protein phosphatase inhibitor 2 does not protect; rate of inactivation is unaffected by EDTA, EGTA, Mg2+, Ca2+; specific protamine kinase inhibitors Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.11.1 cytosol
-
 Bos taurus 5829
-
2.7.11.1 soluble
-
 Bos taurus
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.1 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.1 kidney
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.1 ATP + protamine
-
 Bos taurus ADP + O-phosphoprotamine
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.11.1 30
-
 assay at Bos taurus