Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • King, R.S.; Sharma, V.; Pedersen, L.C.; Kakuta, Y.; Negishi, M.; Duffel, M.W.
    Structure-function modeling of the interactions of N-alkyl-N-hydroxyanilines with rat hepatic aryl sulfotransferase IV (2000), Chem. Res. Toxicol., 13, 1251-1258.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.8.2.9 N-n-butyl-N-hydroxyaniline competitive, reversible Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.8.2.9 0.119
-
 N-hydroxy-N-methylaniline pH 7, 37°C Rattus norvegicus
2.8.2.9 0.161
-
 N-hydroxy-N-n-propylaniline pH 7, 37°C Rattus norvegicus
2.8.2.9 0.65
-
 N-ethyl-N-hydroxyaniline pH 7, 37°C Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.8.2.9 33500
-
 x * 33500, SDS-PAGE Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.9 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.8.2.9 homogeneity Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.2.9 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.8.2.9 0.8 1
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.9 3'-phosphoadenylylsulfate + 2-naphthol
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + 2-naphthyl sulfate
-
 ?
2.8.2.9 3'-phosphoadenylylsulfate + N-ethyl-N-hydroxyaniline
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + ?
-
 ?
2.8.2.9 3'-phosphoadenylylsulfate + N-hydroxy-N-methylaniline
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + ?
-
 ?
2.8.2.9 3'-phosphoadenylylsulfate + N-hydroxy-N-n-propylaniline
-
 Rattus norvegicus adenosine 3',5'-bisphosphate + ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.8.2.9 ? x * 33500, SDS-PAGE Rattus norvegicus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.8.2.9 0.066
-
 N-n-butyl-N-hydroxyaniline pH 7, 37°C Rattus norvegicus