EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.8.2.9 | 1-naphthaldehyde | reversible | Rattus norvegicus | |
2.8.2.9 | 1-naphthoic acid | - |
Rattus norvegicus | |
2.8.2.9 | 1-naphthylacetic acid | competitive with respect to 1-naphththalenemethanol | Rattus norvegicus | |
2.8.2.9 | 2-naphthaldehyde | reversible | Rattus norvegicus | |
2.8.2.9 | 2-naphthoic acid | reversible | Rattus norvegicus | |
2.8.2.9 | 2-naphthylacetic acid | competitive with respect to 1-naphththalenemethanol | Rattus norvegicus | |
2.8.2.9 | 4-chloro-N-hydroxyaniline | at high concentrations | Rattus norvegicus | |
2.8.2.9 | benzoic acid | competitive with respect to 1-naphththalenemethanol | Rattus norvegicus | |
2.8.2.9 | naproxen | competitive with respect to 1-naphththalenemethanol | Rattus norvegicus | |
2.8.2.9 | phenylacetic acid | competitive with respect to 1-naphthalenemethanol | Rattus norvegicus | |
2.8.2.9 | R-(+)-2-methyl-1-phenylpropanol | competitive, reversible inhibitor, stereochemical configuration is important, the other enantiomer acts as substrate | Rattus norvegicus | |
2.8.2.9 | S-(+)-1,2,3,4-tetrahydro-1-naphthol | competitive, reversible inhibitor, stereochemical configuration is important, the other enantiomer acts as substrate | Rattus norvegicus | |
2.8.2.9 | salicylic acid | competitive with respect to 1-naphththalenemethanol | Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.8.2.9 | 0.026 | - |
4-chloro-N-hydroxyaniline | pH 7, 37°C | Rattus norvegicus | |
2.8.2.9 | 0.12 | - |
N-hydroxy-N-methylaniline | pH 7, 37°C | Rattus norvegicus | |
2.8.2.9 | 0.65 | - |
N-hydroxy-N-ethylaniline | pH 7, 37°C | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.8.2.9 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.8.2.9 | liver | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.8.2.9 | (1S)-2-methyl-1-phenylpropan-1-ol | stereochemical configuration is important, the other enantiomer acts as inhibitor | Rattus norvegicus | adenosine 3',5'-bisphosphate + (1S)-2-methyl-1-phenylpropyl sulfate | - |
? | |
2.8.2.9 | 3'-phosphoadenylylsulfate + 4-chloro-N-hydroxyaniline | - |
Rattus norvegicus | adenosine 3',5'-bisphosphate + ? | - |
? | |
2.8.2.9 | 3'-phosphoadenylylsulfate + N-hydroxy-N-ethylaniline | - |
Rattus norvegicus | adenosine 3',5'-bisphosphate + ? | - |
? | |
2.8.2.9 | 3'-phosphoadenylylsulfate + N-hydroxy-N-methylaniline | - |
Rattus norvegicus | adenosine 3',5'-bisphosphate + ? | - |
? | |
2.8.2.9 | additional information | - |
Rattus norvegicus | ? | - |
? | |
2.8.2.9 | R-(-)-1,2,3,4-tetrahydro-1-naphthol | stereochemical configuration is important, the other enantiomer acts as inhibitor | Rattus norvegicus | adenosine 3',5'-bisphosphate + (R)-(-)-1,2,3,4-tetrahydro-1-naphthyl sulfate | - |
? |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.8.2.9 | 0.016 | - |
1-naphthoic acid | pH 7, 37°C | Rattus norvegicus | |
2.8.2.9 | 0.029 | - |
1-naphthaldehyde | pH 7, 37°C | Rattus norvegicus | |
2.8.2.9 | 0.041 | - |
2-naphthoic acid | pH 7, 37°C | Rattus norvegicus | |
2.8.2.9 | 0.067 | - |
salicylic acid | pH 7, 37°C | Rattus norvegicus | |
2.8.2.9 | 0.089 | - |
2-naphthaldehyde | pH 7, 37°C | Rattus norvegicus | |
2.8.2.9 | 0.13 | - |
naproxen | pH 7, 37°C | Rattus norvegicus | |
2.8.2.9 | 0.2 | - |
1-naphthylacetic acid | pH 7, 37°C | Rattus norvegicus | |
2.8.2.9 | 0.28 | - |
benzoic acid | pH 7, 37°C | Rattus norvegicus | |
2.8.2.9 | 0.41 | - |
2-naphthylacetic acid | pH 7, 37°C | Rattus norvegicus | |
2.8.2.9 | 1.1 | - |
phenylacetic acid | pH 7, 37°C | Rattus norvegicus |