EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.4.1.20 | diethylcarbamazine | IC50: 0.05 mM | Homo sapiens | |
4.4.1.20 | NEM | IC50: 0.02 mM | Homo sapiens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.4.1.20 | 0.0056 | - |
leukotriene A4 | pH 7.4, 25°C | Homo sapiens | |
4.4.1.20 | 1.2 | - |
glutathione | pH 7.4, 25°C | Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
4.4.1.20 | membrane | - |
Homo sapiens | 16020 | - |
4.4.1.20 | membrane | - |
Rattus norvegicus | 16020 | - |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.4.1.20 | Homo sapiens | - |
- |
- |
4.4.1.20 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
4.4.1.20 | U-937 cell | monocytic leukemia cell line | Homo sapiens | - |
4.4.1.20 | U-937 cell | dimethyl sulfoxide-differentiated and undifferentiated | Homo sapiens | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
4.4.1.20 | 0.000399 | - |
differentiated cells | Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.4.1.20 | leukotriene A4 + glutathione | - |
Homo sapiens | leukotriene C4 + H2O | - |
? | |
4.4.1.20 | leukotriene A4 + glutathione | - |
Rattus norvegicus | leukotriene C4 + H2O | - |
? |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
4.4.1.20 | 0.02 | - |
IC50: 0.02 mM | Homo sapiens | NEM | |
4.4.1.20 | 0.05 | - |
IC50: 0.05 mM | Homo sapiens | diethylcarbamazine |