EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
4.4.1.20 | A52S | mutation increases the Km-value for the recombinant enzyme for glutathione | Homo sapiens |
4.4.1.20 | N55A | mutation increases the Km-value for the recombinant enzyme for glutathione | Homo sapiens |
4.4.1.20 | R51H | fully active mutant enzyme | Homo sapiens |
4.4.1.20 | R51K | fully active mutant enzyme | Homo sapiens |
4.4.1.20 | V49F | mutation increases the Km-value for the recombinant enzyme for glutathione | Homo sapiens |
4.4.1.20 | Y59F | mutation increases the Km-value for the recombinant enzyme for glutathione | Homo sapiens |
4.4.1.20 | Y93F | mutation increases the Km-value for the recombinant enzyme for glutathione | Homo sapiens |
4.4.1.20 | Y93F | activity of the mutant enzyme is less than 1% of the wild-type enzyme, shift in pH optimum of the residual activity to that of spontaneous conjugation | Homo sapiens |
4.4.1.20 | Y97F | mutation increases the Km-value for the recombinant enzyme for glutathione | Homo sapiens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.4.1.20 | 0.0099 | - |
leukotriene A4 | - |
Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
4.4.1.20 | microsome | - |
Cavia porcellus | - |
- |
4.4.1.20 | microsome | - |
Mus musculus | - |
- |
4.4.1.20 | microsome | - |
Homo sapiens | - |
- |
4.4.1.20 | perinuclear space | - |
Homo sapiens | - |
- |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
4.4.1.20 | 16567 | - |
x * 16567, calculation from nucleotide sequence | Homo sapiens |
4.4.1.20 | 18000 | - |
x * 18000, SDS-PAGE | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.4.1.20 | Cavia porcellus | - |
- |
- |
4.4.1.20 | Homo sapiens | - |
- |
- |
4.4.1.20 | Mus musculus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
4.4.1.20 | eosinophil | - |
Homo sapiens | - |
4.4.1.20 | KG-1 cell | - |
Homo sapiens | - |
4.4.1.20 | lung | - |
Cavia porcellus | - |
4.4.1.20 | lung | - |
Mus musculus | - |
4.4.1.20 | lung | - |
Homo sapiens | - |
4.4.1.20 | mast cell | - |
Mus musculus | - |
4.4.1.20 | mast cell | - |
Homo sapiens | - |
4.4.1.20 | platelet | - |
Homo sapiens | - |
4.4.1.20 | THP-1 cell | monocytic leukemia cell line | Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.4.1.20 | leukotriene A4 + glutathione | - |
Cavia porcellus | leukotriene C4 + H2O | - |
? | |
4.4.1.20 | leukotriene A4 + glutathione | - |
Mus musculus | leukotriene C4 + H2O | - |
? | |
4.4.1.20 | leukotriene A4 + glutathione | - |
Homo sapiens | leukotriene C4 + H2O | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
4.4.1.20 | ? | x * 18000, SDS-PAGE | Homo sapiens |
4.4.1.20 | ? | x * 16567, calculation from nucleotide sequence | Homo sapiens |