BRENDA - Enzyme Database

Studies on the synthesis of CDP-diacylglycerol: stimulation by GTP and inhibition by ATP and fluoride

Sribney, M.; Dove, J.L.; Lyman, E.M.; Biochim. Biophys. Acta 79, 749-755 (1977)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
2.7.7.41
GTP
maximal stimulation at 1 mM; stimulates
Rattus norvegicus
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.7.41
ATP
3 mM 50% inhibition. 5 mM, complete inhibition
Rattus norvegicus
2.7.7.41
F-
20 mM, completely abolishes the stimulatory effect of GTP
Rattus norvegicus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.7.41
microsome
-
Rattus norvegicus
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.7.7.41
Rattus norvegicus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.7.41
liver
-
Rattus norvegicus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.7.41
CTP + phosphatidate
-
643305
Rattus norvegicus
diphosphate + CDPdiacylglycerol
-
-
-
?
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
2.7.7.41
GTP
maximal stimulation at 1 mM; stimulates
Rattus norvegicus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.7.41
ATP
3 mM 50% inhibition. 5 mM, complete inhibition
Rattus norvegicus
2.7.7.41
F-
20 mM, completely abolishes the stimulatory effect of GTP
Rattus norvegicus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.7.41
microsome
-
Rattus norvegicus
-
-
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.7.41
liver
-
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.7.41
CTP + phosphatidate
-
643305
Rattus norvegicus
diphosphate + CDPdiacylglycerol
-
-
-
?