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Literature summary extracted from

  • Topalian, S.L.; Kaneko, S.; Gonzales, M.I.; Bond, G.L.; Ward, Y.; Manley, J.L.
    Identification and functional characterization of neo-poly(A) polymerase, an RNA processing enzyme overexpressed in human tumors (2001), Mol. Cell. Biol., 21, 5614-5623.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
2.7.7.19 medicine enzyme is overexpressed in cancers Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.7.19
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.7.19 nucleus
-
 Homo sapiens 5634
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.7.19 82800
-
 x * 83000, SDS-PAGE, x * 82800, deduced from gene sequence Homo sapiens
2.7.7.19 83000
-
 x * 83000, SDS-PAGE, x * 82800, deduced from gene sequence Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.19 Homo sapiens Q9BWT3
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.7.7.19 additional information no phosphoprotein Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.19 melanoma cell line
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.19 ATP + RNA highly specific for ATP Homo sapiens diphosphate + RNA(A)n
-
 r

Subunits

EC Number Subunits Comment Organism
2.7.7.19 ? x * 83000, SDS-PAGE, x * 82800, deduced from gene sequence Homo sapiens