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Literature summary extracted from

  • Mansbach II, C.M.; Arnold, A.
    CTP:phosphocholine cytidylyltransferase in intestinal mucosa (1986), Biochim. Biophys. Acta, 875, 516-524.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.15 chlorpromazine inhibition of liver enzyme, no inhibition of gut enzyme at 0.08 mM Rattus norvegicus
2.7.7.15 additional information no inhibition by propanolol and tetracaine Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.7.15 cytosol
-
 Rattus norvegicus 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.15 CTP + choline phosphate Rattus norvegicus catalyzes a major rate-limiting step in the biosynthesis of phosphocholine diphosphate + CDPcholine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.15 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.15 intestinal mucosa contains only L-form Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.15 CTP + choline phosphate
-
 Rattus norvegicus diphosphate + CDPcholine
-
 ?
2.7.7.15 CTP + choline phosphate catalyzes a major rate-limiting step in the biosynthesis of phosphocholine Rattus norvegicus diphosphate + CDPcholine
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.7.15 37
-
 assay at Rattus norvegicus