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Literature summary extracted from

  • Gilles, A.M.; Presecan, E.; Vonica, A.; Lascu, I.
    Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme (1991), J. Biol. Chem., 266, 8784-8789.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.4.6 8-bromo-IDP in excess Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.4.6 0.033
-
 8-bromo-IDP isozyme A6, 25°C Homo sapiens
2.7.4.6 0.06
-
 8-bromo-IDP isozyme B6, 25°C Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.7.4.6 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.4.6
-
 Homo sapiens

Renatured (Commentary)

EC Number Renatured (Comment) Organism
2.7.4.6 renaturation of subunit polypeptides A and B generates several isozymes Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.4.6 erythrocyte
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.4.6 550
-
 isozyme A6, 25°C Homo sapiens
2.7.4.6 740
-
 isozyme B6, 25°C Homo sapiens
2.7.4.6 800
-
 native enzyme Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.4.6 ATP + 8-bromo-IDP
-
 Homo sapiens ADP + ?
-
 ?
2.7.4.6 NTP + nucleoside diphosphate
-
 Homo sapiens NDP + NTP
-
 ?