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Literature summary extracted from

  • Del Vecchio, R.L.; Pilch, P.F.
    Phosphatidylinositol 4-kinase is a component of glucose transporter (GLUT 4)-containing vesicles (1991), J. Biol. Chem., 266, 13278-13283.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.1.67 Triton X-100 maximal activity at 0.2% w/v Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.67 adenosine
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.67 plasma membrane
-
 Rattus norvegicus 5886
-
2.7.1.67 transport vesicle glucose-transporter Rattus norvegicus 30133
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.67 ATP + 1-phosphatidyl-1D-myo-inositol Rattus norvegicus phosphatidylinositol 4-kinase is a component of glucose transporter-containing vesicles. It may play a role in defining the fusogenic properties necessary to mediate membrane movement between the glucose transporter vesicles, plasma membranes and micosomes ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.67 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.67 adipocyte
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.67 ATP + 1-phosphatidyl-1D-myo-inositol
-
 Rattus norvegicus ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
-
 ?
2.7.1.67 ATP + 1-phosphatidyl-1D-myo-inositol phosphatidylinositol 4-kinase is a component of glucose transporter-containing vesicles. It may play a role in defining the fusogenic properties necessary to mediate membrane movement between the glucose transporter vesicles, plasma membranes and micosomes Rattus norvegicus ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.7.1.67 0.02 0.03 adenosine
-
 Rattus norvegicus