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Literature summary extracted from

  • Kalin, J.R.; Allen, C.M.
    Lipid activation of undecaprenol kinase from Lactobacillus plantarum (1980), Biochim. Biophys. Acta, 619, 76-89.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.1.66 ditetradecanoylphosphatidylcholine good activator Lactiplantibacillus plantarum
2.7.1.66 lysophosphatidylglycerol good activator Lactiplantibacillus plantarum
2.7.1.66 Phospholipid cofactor requirements for endogenous and exogenous phospholipids. Enzyme requires a fluid lipid surface for activity, lysophosphatidylglycerol and ditetradecanoylphosphatidylcholine are the best activators Lactiplantibacillus plantarum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.1.66 0.0055
-
 dolichol
-
 Lactiplantibacillus plantarum
2.7.1.66 0.008
-
 undecaprenol
-
 Lactiplantibacillus plantarum

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.66 membrane
-
 Lactiplantibacillus plantarum 16020
-

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.66 Lactiplantibacillus plantarum
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.7.1.66 lipoprotein requirements for endogenous and exogenous phospholipids. Enzyme requires a fluid lipid surface for activity, lysophosphatidylglycerol and ditetradecanoylphosphatidylcholine are the best activators Lactiplantibacillus plantarum

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.66 partial Lactiplantibacillus plantarum

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.1.66 additional information
-
-
 Lactiplantibacillus plantarum

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.66 ATP + (E,E,E)-geranylgeraniol 28% of the activity with ATP Lactiplantibacillus plantarum ADP + (E,E,E)-geranylgeraniyl phosphate
-
 ?
2.7.1.66 ATP + dolichol 26% of the activity with undecaprenol Lactiplantibacillus plantarum ADP + dolichyl phosphate
-
 ?
2.7.1.66 ATP + solanesol about 85% of the activity with undecaprenol Lactiplantibacillus plantarum ADP + solanesyl phosphate
-
 ?
2.7.1.66 ATP + undecaprenol best substrate Lactiplantibacillus plantarum ADP + undecaprenyl monophosphate
-
 ?