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Literature summary extracted from

  • Suarez, D.; Garcia-Peregrin, E.; Mayor, F.
    Mevalonate kinase from Pinus pinaster seedlings (1974), Phytochemistry, 13, 1059-1063.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.36 EDTA 10 mM, almost complete inhibition Pinus pinaster
2.7.1.36 Mn2+ inhibition at 10 mM in crude extracts Pinus pinaster

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.1.36 0.08
-
 mevalonate pH 7.9, 37°C Pinus pinaster
2.7.1.36 0.14
-
 ATP pH 7.9, 37°C Pinus pinaster

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.36 Pinus pinaster
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.36 protamine sulfate, ammonium sulfate, Sephadex G-100 Pinus pinaster

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.36 seedling
-
 Pinus pinaster
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.1.36 additional information
-
 0.132 dpm/mg Pinus pinaster

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.36 ATP + mevalonate no activity with GTP Pinus pinaster ADP + phosphomevalonate
-
 ?
2.7.1.36 ATP + mevalonate no activity with ITP, UTP and ADP Pinus pinaster ADP + phosphomevalonate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.1.36 37
-
 assay at Pinus pinaster

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.1.36 7.8 8
-
 Pinus pinaster