EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.32 | Acetylcholine | stimulates | Rattus norvegicus | |
2.7.1.32 | putrescine | slight stimulation | Rattus norvegicus | |
2.7.1.32 | spermidine | stimulates | Rattus norvegicus | |
2.7.1.32 | spermine | stimulates | Rattus norvegicus | |
2.7.1.32 | spermine | in presence of sufficient amounts of Mg2+ | Rattus norvegicus |
EC Number | General Stability | Organism |
---|---|---|
2.7.1.32 | very stable, even at a low protein concentration, 0.001 mg/ml | Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.1.32 | additional information | - |
additional information | - |
Rattus norvegicus | |
2.7.1.32 | 0.022 | - |
N,N-dimethylethanolamine | 30°C | Rattus norvegicus | |
2.7.1.32 | 0.118 | - |
N-Monomethylethanolamine | 30°C | Rattus norvegicus | |
2.7.1.32 | 0.208 | - |
N,N-Dimethylaminopropanol | 30°C | Rattus norvegicus | |
2.7.1.32 | 0.4 | - |
N,N-Diisopropylethanolamine | 30°C | Rattus norvegicus | |
2.7.1.32 | 0.444 | - |
beta-Methylcholine | 30°C | Rattus norvegicus | |
2.7.1.32 | 0.787 | - |
ethanolamine | 30°C | Rattus norvegicus | |
2.7.1.32 | 1.2 | - |
ethanolamine | 30°C | Rattus norvegicus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.32 | Carpronium chloride | stimulates | Rattus norvegicus | |
2.7.1.32 | Chlorocholine chloride | stimulates | Rattus norvegicus | |
2.7.1.32 | K+ | stimulates | Rattus norvegicus | |
2.7.1.32 | Li+ | stimulates | Rattus norvegicus | |
2.7.1.32 | Mg2+ | required | Rattus norvegicus | |
2.7.1.32 | Mg2+ | stimulates most efficiently of divalent cations | Rattus norvegicus | |
2.7.1.32 | Mg2+ | maximal activity at equimolar concentration of ATP and Mg2+ | Rattus norvegicus | |
2.7.1.32 | Mn2+ | one-sixth as effective as Mg2+ | Rattus norvegicus | |
2.7.1.32 | additional information | Co2+, Cd2+: almost completely ineffective, Ca2+, Ni2+, Zn2+: totally ineffective | Rattus norvegicus | |
2.7.1.32 | Na+ | stimulates | Rattus norvegicus | |
2.7.1.32 | NH4+ | stimulates | Rattus norvegicus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.7.1.32 | 44000 | - |
2 * 44000, brain enzyme, SDS-PAGE | Rattus norvegicus |
2.7.1.32 | 87600 | - |
sucrose density gradient centrifugation, gel filtration | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.32 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.7.1.32 | - |
Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.1.32 | brain | - |
Rattus norvegicus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.7.1.32 | 40.4 | - |
30°C | Rattus norvegicus |
EC Number | Storage Stability | Organism |
---|---|---|
2.7.1.32 | 4°C, stable for at least 1 month | Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.32 | ATP + choline | - |
Rattus norvegicus | ADP + O-phosphocholine | - |
? | |
2.7.1.32 | beta-methylcholine + ATP | - |
Rattus norvegicus | ADP + beta-methylcholine phosphate | - |
? | |
2.7.1.32 | CTP + choline | 12% of the activity with ATP | Rattus norvegicus | CDP + choline phosphate | - |
? | |
2.7.1.32 | ethanolamine + ATP | - |
Rattus norvegicus | ADP + ethanolamine phosphate | - |
? | |
2.7.1.32 | GTP + choline | poor substrate | Rattus norvegicus | GDP + choline phosphate | - |
? | |
2.7.1.32 | N,N-diethylethanolamine + ATP | - |
Rattus norvegicus | ADP + N,N-diethylethanolamine phosphate | - |
? | |
2.7.1.32 | N,N-diisopropylethanolamine + ATP | - |
Rattus norvegicus | ADP + N,N-diisopropylethanolamine phosphate | - |
? | |
2.7.1.32 | N,N-dimethylaminopropanol + ATP | - |
Rattus norvegicus | ADP + N,N-dimethylaminopropyl phosphate | - |
? | |
2.7.1.32 | N,N-dimethylethanolamine + ATP | - |
Rattus norvegicus | ADP + N,N-dimethylethanolamine phosphate | - |
? | |
2.7.1.32 | N-methylethanolamine + ATP | - |
Rattus norvegicus | ADP + N-methylethanolamine phosphate | - |
? | |
2.7.1.32 | N-monomethylethanolamine + ATP | - |
Rattus norvegicus | ADP + N-monomethylethanolamine phosphate | - |
? | |
2.7.1.32 | UTP + choline | poor substrate | Rattus norvegicus | UDP + choline phosphate | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.7.1.32 | dimer | 2 * 44000, brain enzyme, SDS-PAGE | Rattus norvegicus |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
2.7.1.32 | 30 | - |
assay at | Rattus norvegicus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.7.1.32 | 10.5 | - |
- |
Rattus norvegicus |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
2.7.1.32 | 10.5 | - |
increase of activity up to | Rattus norvegicus |