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Literature summary extracted from

  • Raushel, F.M.; Cleland, W.W.
    The substrate and anomeric specificity of fructokinase (1973), J. Biol. Chem., 248, 8174-8177.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.3 2,5-Anhydro-D-xylitol
-
 Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.1.3 0.31
-
 2,5-anhydro-D-mannose 25°C, pH 7.5, MgATP2-: 2mM Saccharomyces cerevisiae
2.7.1.3 0.4
-
 L-sorbose 25°C, pH 7.5, MgATP2-: 4mM Bos taurus
2.7.1.3 0.5
-
 D-fructose 25°C, pH 7.5, MgATP2-: 4mM Bos taurus
2.7.1.3 0.9
-
 D-tagatose 25°C, pH 7.5, MgATP2-: 4mM Bos taurus
2.7.1.3 1.5
-
 2,5-anhydro-D-mannose 25°C, pH 7.5, MgATP2-: 4mM Bos taurus
2.7.1.3 1.7
-
 2,5-anhydro-D-mannitol 25°C, pH 7.5, MgATP2-2-: 4mM Bos taurus
2.7.1.3 5.9
-
 2,5-anhydro-D-glucitol 25°C, pH 7.5, MgATP2-2-: 4mM Bos taurus
2.7.1.3 6.3
-
 2,5-anhydro-D-mannitol 25°C, pH 7.5, MgATP2-2-: 2mM Saccharomyces cerevisiae
2.7.1.3 47
-
 2,5-anhydro-D-glucitol 25°C, pH 7.5, MgATP2-2-: 2mM Saccharomyces cerevisiae
2.7.1.3 67
-
 2,5-anhydro-D-lyxitol 25°C, pH 7.5, MgATP2-2-: 4mM Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.3 ATP + D-fructose Saccharomyces cerevisiae
-
 ADP + D-fructose 1-phosphate
-
 ?
2.7.1.3 ATP + D-fructose Bos taurus
-
 ADP + D-fructose 1-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.3 Bos taurus
-
-
-
2.7.1.3 Saccharomyces cerevisiae
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.3 liver
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.3 ATP + 2,5-anhydro-D-glucitol
-
 Saccharomyces cerevisiae ?
-
 ?
2.7.1.3 ATP + 2,5-anhydro-D-glucitol
-
 Bos taurus ?
-
 ?
2.7.1.3 ATP + 2,5-anhydro-D-lyxitol
-
 Bos taurus ?
-
 ?
2.7.1.3 ATP + 2,5-anhydro-D-mannitol
-
 Saccharomyces cerevisiae ?
-
 ?
2.7.1.3 ATP + 2,5-anhydro-D-mannitol
-
 Bos taurus ?
-
 ?
2.7.1.3 ATP + 2,5-anhydro-D-mannose
-
 Saccharomyces cerevisiae ?
-
 ?
2.7.1.3 ATP + 2,5-anhydro-D-mannose
-
 Bos taurus ?
-
 ?
2.7.1.3 ATP + D-fructose
-
 Saccharomyces cerevisiae ADP + D-fructose 1-phosphate
-
 ?
2.7.1.3 ATP + D-fructose
-
 Bos taurus ADP + D-fructose 1-phosphate
-
 ?
2.7.1.3 ATP + D-fructose specific for beta-furanose anomer Bos taurus ADP + D-fructose 1-phosphate
-
 ?
2.7.1.3 ATP + D-tagatose
-
 Bos taurus ?
-
 ?
2.7.1.3 ATP + L-sorbose specific for alpha anomer Bos taurus ?
-
 ?
2.7.1.3 additional information not: 2,6-anhydro-D-glucitol Bos taurus ?
-
 ?
2.7.1.3 additional information specificity of fructokinase is for a tetrahydrofuran ring with beta-D-(or alpha-L-)configuration at position 2, L-configuration at position 3 and either D- or L-configuration at position 4 and 5 Bos taurus ?
-
 ?
2.7.1.3 additional information not: 2,6-anhydro-D-mannitol Bos taurus ?
-
 ?