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Literature summary extracted from

  • Parks, R.E.; Ben-Gershom, E.; Lardy, H.E.
    Liver fructokinase (1957), J. Biol. Chem., 227, 231-242.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.3 ADP strong, noncompetitive Bos taurus
2.7.1.3 ATP
-
 Bos taurus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.3 Cs+ absolute requirement for both monovalent and divalent cations, when Mg2+ fills the requirement for divalent cation, K+ and Rb+ are the most active monovalent cations, NH4+, Na+, Cs+ and Li+ are decreasingly active Bos taurus
2.7.1.3 K+ absolute requirement for both monovalent and divalent cations, when Mg2+ fills the requirement for divalent cation, K+ and Rb+ are the most active monovalent cations Bos taurus
2.7.1.3 K+ NH4+, Na+, Cs+ and Li+ are decreasingly active Bos taurus
2.7.1.3 Li+ absolute requirement for both monovalent and divalent cations, when Mg2+ fills the requirement for divalent cation, K+ and Rb+ are the most active monovalent cations, NH4+, Na+, Cs+ and Li+ are decreasingly active Bos taurus
2.7.1.3 Mg2+ absolute requirement for both monovalent and divalent cations, for optimal activity the concentration of Mg2+ must equal or exceed the concentration of ATP Bos taurus
2.7.1.3 Na+ absolute requirement for both monovalent and divalent cations, when Mg2+ fills the requirement for divalent cation, K+ and Rb+ are the most active monovalent cations, NH4+, Na+, Cs+ and Li+ are decreasingly active Bos taurus
2.7.1.3 NH4+ absolute requirement for both monovalent and divalent cations, when Mg2+ fills the requirement for divalent cation, K+ and Rb+ are the most active monovalent cations, NH4+, Na+, Cs+ and Li+ are decreasingly active Bos taurus
2.7.1.3 Rb+ absolute requirement for both monovalent and divalent cations, when Mg2+ fills the requirement for divalent cation, K+ and Rb+ are the most active monovalent cations, NH4+, Na+, Cs+ and Li+ are decreasingly active Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.3 ATP + D-fructose Bos taurus D-fructose metabolism ADP + D-fructose 1-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.3 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.3
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.3 liver
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.3 ATP + D-fructose
-
 Bos taurus ADP + D-fructose 1-phosphate
-
 ?
2.7.1.3 ATP + D-fructose D-fructose metabolism Bos taurus ADP + D-fructose 1-phosphate
-
 ?
2.7.1.3 additional information not: UTP Bos taurus ?
-
 ?
2.7.1.3 additional information not: ITP Bos taurus ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.1.3 5.5 7.8
-
 Bos taurus