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Literature summary extracted from

  • Cataldi, A.; Di Pietro, R.; Centurione, L.; Grilli, A.; Cutroneo, G.; Miscia, S.
    Phosphatidylinositol-3-kinase activation and atypical protein kinase C z phosphorylation characterize the DMSO signaling in erythroleukemia cells (2000), Cell. Signal., 12, 667-672.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.137 LY294002
-
 Mus musculus
2.7.1.137 Wortmannin
-
 Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.137 additional information Mus musculus PI-3-kinase might be involved in the induction of erythroid differentiation, possibly engaging a protein kinase C z as downstream effector ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.137 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.137 cell culture Friend erythroleukemia cells Mus musculus
-
2.7.1.137 Friend erythroleukemia cell line
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.137 ATP + 1-phosphatidylinositol
-
 Mus musculus ADP + phosphatidylinositol 3-phosphate
-
 ?
2.7.1.137 additional information PI-3-kinase might be involved in the induction of erythroid differentiation, possibly engaging a protein kinase C z as downstream effector Mus musculus ?
-
 ?