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Literature summary extracted from

  • Gamble, J.; Lopaschuk, G.D.
    Insulin inhibition of 5' adenosine monophosphate-activated protein kinase in the heart results in activation of acetyl coenzyme A carboxylase and inhibition of fatty acid oxidation (1997), Metabolism, 46, 1270-1274.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.27 AMP
-
 Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.27 Insulin
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.27 ATP + [acetyl-CoA carboxylase] Rattus norvegicus regulation of acetyl-CoA carboxylase in muscle at metabolic stress conditions ADP + [acetyl-CoA carboxylase] phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.27 Rattus norvegicus
-
 male sprague-dawley rats
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.27 heart
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.27 ATP + [acetyl-CoA carboxylase]
-
 Rattus norvegicus ADP + [acetyl-CoA carboxylase] phosphate
-
 ?
2.7.11.27 ATP + [acetyl-CoA carboxylase] regulation of acetyl-CoA carboxylase in muscle at metabolic stress conditions Rattus norvegicus ADP + [acetyl-CoA carboxylase] phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.27 5'-AMP activated protein kinase
-
 Rattus norvegicus