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Literature summary extracted from

  • Takazawa, K.; Erneux, C.
    Inhibition of inositol 1,4,5-trisphosphate by heparin: basal and Ca2+/calmodulin-stimulated activity (1989), Biochem. J., 261, 1059.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.127 heparin mixed-type inhibition Bos taurus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.127 Ca2+ up to 30fold stimulation by Ca2+/calmodulin Bos taurus
2.7.1.127 Ca2+ activation by Ca2+/calmodulin Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.127 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.127
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.127 brain
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.127 ATP + 1D-myo-inositol 1,4,5-trisphosphate
-
 Bos taurus ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.1.127 ATP
-
 Bos taurus
2.7.1.127 Calmodulin activation by Ca2+/calmodulin Bos taurus
2.7.1.127 Calmodulin up to 30fold stimulation by Ca2+/calmodulin Bos taurus